Lineage for Protein: Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 952974Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 952975Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 954798Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (4 proteins)
  6. 954843Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (5 species)
    contains an extra alpha-helical domain

Species:

  1. 954844Human coronavirus 229E [TaxId:11137] [89348] (2 PDB entries)
    1. Domains for 1p9s:
      1. 954847Domain d1p9sa_: 1p9s A: [87999]
        complexed with dio
      2. 954848Domain d1p9sb_: 1p9s B: [88000]
        complexed with dio
    2. Domains for 2zu2:
      1. 954845Domain d2zu2a_: 2zu2 A: [171525]
        automated match to d1p9sa_
        complexed with dtz, mpd
      2. 954846Domain d2zu2b_: 2zu2 B: [171526]
        automated match to d1p9sa_
        complexed with dtz, mpd
  2. 954849Human coronavirus [TaxId:443239] [188597] (1 PDB entry)
  3. 954854Sars coronavirus sin2774 [TaxId:235410] [187498] (2 PDB entries)
    1. Domain for 2bx3:
    2. Domain for 2bx4:
  4. 954857SARS coronavirus [TaxId:227859] [89349] (55 PDB entries)
    1. Domains for 1q2w:
      1. 954875Domain d1q2wa_: 1q2w A: [88355]
        complexed with mpd
      2. 954876Domain d1q2wb_: 1q2w B: [88356]
        complexed with mpd
    2. Domains for 1uj1:
      1. 954885Domain d1uj1a_: 1uj1 A: [99450]
      2. 954886Domain d1uj1b_: 1uj1 B: [99451]
    3. Domains for 1uk2:
      1. 954905Domain d1uk2a_: 1uk2 A: [99481]
      2. 954906Domain d1uk2b_: 1uk2 B: [99482]
    4. Domains for 1uk3:
      1. 954912Domain d1uk3a_: 1uk3 A: [99483]
      2. 954913Domain d1uk3b_: 1uk3 B: [99484]
    5. Domains for 1uk4:
      1. 954914Domain d1uk4a_: 1uk4 A: [99485]
        complexed with ato
      2. 954915Domain d1uk4b_: 1uk4 B: [99486]
        complexed with ato
    6. Domain for 1z1i:
    7. Domains for 1z1j:
      1. 954930Domain d1z1ja_: 1z1j A: [162357]
        automated match to d1uj1b_
        mutant
      2. 954931Domain d1z1jb_: 1z1j B: [162358]
        automated match to d1uj1b_
        mutant
    8. Domain for 2a5a:
    9. Domain for 2a5i:
    10. Domains for 2a5k:
      1. 954897Domain d2a5ka_: 2a5k A: [162694]
        automated match to d1uj1b_
        complexed with azp
      2. 954898Domain d2a5kb_: 2a5k B: [162695]
        automated match to d1uj1b_
        complexed with azp
    11. Domain for 2alv:
    12. Domain for 2c3s:
    13. Domains for 2duc:
      1. 954861Domain d2duca_: 2duc A: [146586]
        automated match to d1uj1b_
      2. 954862Domain d2ducb_: 2duc B: [146587]
        automated match to d1uj1b_
    14. Domains for 2gt7:
      1. 954867Domain d2gt7a_: 2gt7 A: [164833]
        automated match to d1uj1b_
        complexed with mes
      2. 954868Domain d2gt7b_: 2gt7 B: [164834]
        automated match to d1uj1b_
        complexed with mes
    15. Domain for 2gt8:
    16. Domain for 2gtb:
    17. Domain for 2gx4:
    18. Domain for 2gz7:
    19. Domain for 2gz8:
    20. Domain for 2gz9:
    21. Domain for 2h2z:
    22. Domain for 2hob:
    23. Domains for 2op9:
      1. 954864Domain d2op9a_: 2op9 A: [148961]
        automated match to d1q2wb_
        complexed with wr1
      2. 954865Domain d2op9b_: 2op9 B: [148962]
        automated match to d1q2wb_
        complexed with wr1
    24. Domain for 2pwx:
    25. Domains for 2q6g:
      1. 954909Domain d2q6ga_: 2q6g A: [167455]
        automated match to d1uj1b_
        mutant
      2. 954910Domain d2q6gb_: 2q6g B: [167456]
        automated match to d1uj1b_
        mutant
    26. Domains for 2qc2:
      1. 954919Domain d2qc2a_: 2qc2 A: [167515]
        automated match to d1uj1b_
        mutant
      2. 954920Domain d2qc2b_: 2qc2 B: [167516]
        automated match to d1uj1b_
        mutant
    27. Domain for 2qcy:
    28. Domain for 2qiq:
    29. Domain for 2v6n:
    30. Domain for 2z3c:
    31. Domain for 2z3d:
    32. Domain for 2z3e:
    33. Domain for 2z94:
    34. Domain for 2z9g:
    35. Domains for 2z9j:
      1. 954882Domain d2z9ja_: 2z9j A: [154254]
        automated match to d1uj1b_
        protein/RNA complex; complexed with dms, dtz
      2. 954883Domain d2z9jb_: 2z9j B: [154255]
        automated match to d1uj1b_
        protein/RNA complex; complexed with dms, dtz
    36. Domains for 2z9k:
      1. 954871Domain d2z9ka_: 2z9k A: [154256]
        automated match to d1uj1b_
        protein/RNA complex; complexed with dms, doz
      2. 954872Domain d2z9kb_: 2z9k B: [154257]
        automated match to d1uj1b_
        protein/RNA complex; complexed with dms, doz
    37. Domains for 2z9l:
      1. 954893Domain d2z9la_: 2z9l A: [154258]
        automated match to d1uj1b_
        complexed with daz, dms
      2. 954894Domain d2z9lb_: 2z9l B: [154259]
        automated match to d1uj1b_
        complexed with daz, dms
    38. Domain for 2zu4:
    39. Domain for 2zu5:
    40. Domains for 3atw:
      1. 954925Domain d3atwa_: 3atw A: [172333]
        automated match to d1uj1b_
      2. 954926Domain d3atwb_: 3atw B: [172334]
        automated match to d1uj1b_
    41. Domain for 3avz:
    42. Domain for 3aw0:
    43. Domains for 3aw1:
      1. 954916Domain d3aw1a_: 3aw1 A: [172360]
        automated match to d1uj1b_
        mutant
      2. 954917Domain d3aw1b_: 3aw1 B: [172361]
        automated match to d1uj1b_
        mutant
    44. Domain for 3d62:
    45. Domain for 3f9e:
    46. Domains for 3f9f:
      1. 954903Domain d3f9fa_: 3f9f A: [175591]
        automated match to d1uj1b_
        mutant
      2. 954904Domain d3f9fb_: 3f9f B: [175592]
        automated match to d1uj1b_
        mutant
    47. Domains for 3f9g:
      1. 954921Domain d3f9ga_: 3f9g A: [175593]
        automated match to d1q2wb_
        mutant
      2. 954922Domain d3f9gb_: 3f9g B: [175594]
        automated match to d1q2wb_
        mutant
    48. Domains for 3f9h:
      1. 954927Domain d3f9ha_: 3f9h A: [175595]
        automated match to d1uj1b_
        mutant
      2. 954928Domain d3f9hb_: 3f9h B: [175596]
        automated match to d1uj1b_
        mutant
    49. Domain for 3fzd:
    50. Domains for 3m3s:
      1. 954901Domain d3m3sa_: 3m3s A: [180804]
        automated match to d1uj1b_
        mutant
      2. 954902Domain d3m3sb_: 3m3s B: [180805]
        automated match to d1uj1b_
        mutant
    51. Domain for 3sn8:
    52. Domain for 3snb:
    53. Domain for 3snc:
    54. Domains for 3snd:
      1. 954873Domain d3snda_: 3snd A: [185446]
        automated match to d1uj1b_
        complexed with mrd
      2. 954874Domain d3sndb_: 3snd B: [185447]
        automated match to d1uj1b_
        complexed with mrd
    55. Domain for 3sne:
  5. 954935Transmissible gastroenteritis virus [TaxId:11149] [74980] (3 PDB entries)
    1. Domains for 1lvo:
      1. 954936Domain d1lvoa_: 1lvo A: [74284]
        complexed with dio, mrd, so4
      2. 954937Domain d1lvob_: 1lvo B: [74285]
        complexed with dio, mrd, so4
      3. 954938Domain d1lvoc_: 1lvo C: [74286]
        complexed with dio, mrd, so4
      4. 954939Domain d1lvod_: 1lvo D: [74287]
        complexed with dio, mrd, so4
      5. 954940Domain d1lvoe_: 1lvo E: [74288]
        complexed with dio, mrd, so4
      6. 954941Domain d1lvof_: 1lvo F: [74289]
        complexed with dio, mrd, so4
    2. Domains for 1p9u:
      1. 954942Domain d1p9ua_: 1p9u A: [88001]
        complexed with mrd, so4
      2. 954943Domain d1p9ub_: 1p9u B: [88002]
        complexed with mrd, so4
      3. 954944Domain d1p9uc_: 1p9u C: [88003]
        complexed with mrd, so4
      4. 954945Domain d1p9ud_: 1p9u D: [88004]
        complexed with mrd, so4
      5. 954946Domain d1p9ue_: 1p9u E: [88005]
        complexed with mrd, so4
      6. 954947Domain d1p9uf_: 1p9u F: [88006]
        complexed with mrd, so4
    3. Domains for 2amp:
      1. 954948Domain d2ampa_: 2amp A: [127021]
        automated match to d1lvod_
        complexed with i12
      2. 954949Domain d2ampb_: 2amp B: [127022]
        automated match to d1lvod_
        complexed with i12

More info for Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) from b.47.1.4: Viral cysteine protease of trypsin fold

Timeline for Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) from b.47.1.4: Viral cysteine protease of trypsin fold: