SCOPe 2.01: Family b.36.1.4: HtrA-like serine proteases

Lineage for Family b.36.1.4: HtrA-like serine proteases

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.36: PDZ domain-like [50155] (1 superfamily)
   contains barrel, partly opened; n*=4, S*=8; meander; capped by alpha-helix

4. Superfamily b.36.1: PDZ domain-like [50156] (7 families)
   peptide-binding domain

5. Family b.36.1.4: HtrA-like serine proteases [74933] (4 proteins)

Proteins:

1. Mitochondrial serine protease HtrA2 [74936] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [74937] (2 PDB entries)

2. Protease Do (DegP, HtrA), C-terminal domains [74934] (1 species)
   duplication: tandem repeat of two PDZ domains

   • Species Escherichia coli [TaxId:562] [74935] (3 PDB entries)

3. Protease PepD [141288] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [141289] (2 PDB entries)
     Uniprot O53896 375-462
     Rv0983

4. Stress sensor protease DegS, C-terminal domain [110188] (1 species)

   • Species Escherichia coli [TaxId:562] [110189] (5 PDB entries)
     Uniprot P31137 37-354 ! Uniprot P31137

More info for Family b.36.1.4: HtrA-like serine proteases

Timeline for Family b.36.1.4: HtrA-like serine proteases:

• Family b.36.1.4: HtrA-like serine proteases first appeared in SCOP 1.61
  
• Family b.36.1.4: HtrA-like serine proteases appears in SCOP 1.75
  
• Family b.36.1.4: HtrA-like serine proteases appears in SCOPe 2.02
  
• Family b.36.1.4: HtrA-like serine proteases appears in the current release, SCOPe 2.08