Lineage for Species: Human herpesvirus 5 [TaxId: 10359]
- Root: SCOPe 2.07
Class a: All alpha proteins [46456] (289 folds) 
Fold a.26: 4-helical cytokines [47265] (1 superfamily)
core: 4 helices; bundle, closed; left-handed twist; 2 crossover connectionsSuperfamily a.26.1: 4-helical cytokines [47266] (4 families) 
there are two different topoisomers of this fold with different entanglements of the two crossover connections
Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 proteins)
contains an additional helix in one of the crossover connectionsProtein Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) [47306] (3 species)
intertwined dimer, similar to interferon-gamma
Species Human herpesvirus 5 [TaxId:10359] [74708] (1 PDB entry)
PDB entry in Species: Human herpesvirus 5 [TaxId: 10359]:
- Domain(s) for 1lqs:
Domain d1lqsl_: 1lqs L: [74192]
Other proteins in same PDB: d1lqsr1, d1lqsr2, d1lqss1, d1lqss2
complexed with nag
Domain d1lqsm_: 1lqs M: [74193]
Other proteins in same PDB: d1lqsr1, d1lqsr2, d1lqss1, d1lqss2
complexed with nag
More info for Species Human herpesvirus 5 [TaxId:10359] from a.26.1.3 Interleukin-10 (cytokine synthesis inhibitory factor, CSIF)
Timeline for Species Human herpesvirus 5 [TaxId:10359] from a.26.1.3 Interleukin-10 (cytokine synthesis inhibitory factor, CSIF):
- Species Human herpesvirus 5 [TaxId:10359] from a.26.1.3 Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) first appeared in SCOP 1.61
- Species Human herpesvirus 5 [TaxId:10359] from a.26.1.3 Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) appears in SCOPe 2.06
- Species Human herpesvirus 5 [TaxId:10359] from a.26.1.3 Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) appears in the current release, SCOPe 2.08