Lineage for Species: Human herpesvirus 5 [TaxId: 10359]

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991729Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 protein domains)
    contains an additional helix in one of the crossover connections
  6. 1991795Protein Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) [47306] (3 species)
    intertwined dimer, similar to interferon-gamma
  7. 1991808Species Human herpesvirus 5 [TaxId:10359] [74708] (1 PDB entry)

PDB entry in Species: Human herpesvirus 5 [TaxId: 10359]:

More info for Species Human herpesvirus 5 [TaxId:10359] from a.26.1.3 Interleukin-10 (cytokine synthesis inhibitory factor, CSIF)

Timeline for Species Human herpesvirus 5 [TaxId:10359] from a.26.1.3 Interleukin-10 (cytokine synthesis inhibitory factor, CSIF):