SCOP 1.69: Domain d1lo3h1: 1lo3 H:1-119

Lineage for d1lo3h1 (1lo3 H:1-119)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 2.1 [TaxId:10090] [88549] (16 PDB entries)

8. Domain d1lo3h1: 1lo3 H:1-119 [74131]
   Other proteins in same PDB: d1lo3h2, d1lo3l1, d1lo3l2, d1lo3x1, d1lo3x2, d1lo3y2
   part of retro Diels-Alder catalytic Fab 9D9

Details for d1lo3h1

PDB Entry: 1lo3, 2.3 Å

PDB Description: Retro-Diels-Alderase Catalytic Antibody: Product Analogue

SCOP Domain Sequences for d1lo3h1:

Sequence; same for both SEQRES and ATOM records:

>d1lo3h1 b.1.1.1 (H:1-119) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 2.1}
evklvesggglvkpggslklscaasgfsfrnygmswvrqtpekrlewvasisyggliyyp
dsikgrftisrdiaqnilylqmsslrsedtamyhcirgdsflvwftfwgqgtlvtvsa

Timeline for d1lo3h1:

• d1lo3h1 first appeared in SCOP 1.61
  
• d1lo3h1 appears in SCOP 1.67
  
• d1lo3h1 appears in SCOP 1.71
  
• d1lo3h1 appears in the current release, SCOPe 2.08