SCOPe 2.03: Domain d1ld7a_: 1ld7 A:

Lineage for d1ld7a_ (1ld7 A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (1 family)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (2 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69093] (13 PDB entries)
   Uniprot P49354

8. Domain d1ld7a_: 1ld7 A: [73836]
   Other proteins in same PDB: d1ld7b_
   complexed with fpp, suc, u66, zn

Details for d1ld7a_

PDB Entry: 1ld7, 2 Å

PDB Description: co-crystal structure of human farnesyltransferase with farnesyldiphosphate and inhibitor compound 66

PDB Compounds: (A:) protein farnesyltransferase alpha subunit

SCOPe Domain Sequences for d1ld7a_:

Sequence; same for both SEQRES and ATOM records:

>d1ld7a_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Human (Homo sapiens) [TaxId: 9606]}
fvsldspsyvlyrdraewadidpvpqndgpnpvvqiiysdkfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllkslqkdlheemnyitaiieeqpknyqvwhhrrv
lvewlrdpsqelefiadilnqdaknyhawqhrqwviqefklwdnelqyvdqllkedvrnn
svwnqryfvisnttgyndravlerevqytlemiklvphnesawnylkgilqdrglskypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskh

Timeline for d1ld7a_:

• d1ld7a_ first appeared in SCOP 1.61
  
• d1ld7a_ appears in SCOPe 2.02
  
• d1ld7a_ appears in SCOPe 2.04
  
• d1ld7a_ appears in the current release, SCOPe 2.08