SCOP 1.73: Domain d1l8cb_: 1l8c B:

Lineage for d1l8cb_ (1l8c B:)

1. Root: SCOP 1.73

2. Class j: Peptides [58231] (120 folds)

3. Fold j.96: Transactivation domain [81275] (1 superfamily)

4. Superfamily j.96.1: Transactivation domain [74800] (1 family)

5. Family j.96.1.1: Transactivation domain [74801] (2 proteins)

6. Protein C-terminal activation domain (CTAD) of HIF-1alpha [74802] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [74803] (4 PDB entries)

8. Domain d1l8cb_: 1l8c B: [73686]
   Other proteins in same PDB: d1l8ca_
   complexed with TAZ1 domain of mouse CBP
   complexed with zn

Details for d1l8cb_

PDB Entry: 1l8c

PDB Description: structural basis for hif-1alpha/cbp recognition in the cellular hypoxic response

PDB Compounds: (B:) Hypoxia-inducible factor 1 alpha

SCOP Domain Sequences for d1l8cb_:

Sequence; same for both SEQRES and ATOM records:

>d1l8cb_ j.96.1.1 (B:) C-terminal activation domain (CTAD) of HIF-1alpha {Human (Homo sapiens) [TaxId: 9606]}
sdlacrllgqsmdesglpqltsydcevnapiqgsrnllqgeellraldqvn

Timeline for d1l8cb_:

• d1l8cb_ first appeared in SCOP 1.61
  
• d1l8cb_ appears in SCOP 1.71
  
• d1l8cb_ appears in SCOP 1.75
  
• d1l8cb_ appears in the current release, SCOPe 2.08