Lineage for d1l7il2 (1l7i L:108-214)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2745637Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
  6. 2748802Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)
  7. 2748803Species Human (Homo sapiens) [TaxId:9606] [88569] (147 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody
  8. 2748807Domain d1l7il2: 1l7i L:108-214 [73659]
    Other proteins in same PDB: d1l7ih1, d1l7ih2, d1l7il1
    part of humanized anti-ERBb2 Fab 2C4
    complexed with so4

Details for d1l7il2

PDB Entry: 1l7i (more details), 1.8 Å

PDB Description: Crystal Structure of the anti-ErbB2 Fab2C4
PDB Compounds: (L:) chimera of Fab2C4: "humanized" murine monoclonal antibody

SCOPe Domain Sequences for d1l7il2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1l7il2 b.1.1.2 (L:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1l7il2:

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Timeline for d1l7il2:

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