SCOPe 2.07: Domain d1l2ia_: 1l2i A:

Lineage for d1l2ia_ (1l2i A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (82 PDB entries)
   Uniprot P03372 307-551

8. Domain d1l2ia_: 1l2i A: [73503]
   complexed with cl, etc

Details for d1l2ia_

PDB Entry: 1l2i, 1.95 Å

PDB Description: human estrogen receptor alpha ligand-binding domain in complex with (r,r)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol and a glucocorticoid receptor interacting protein 1 nr box ii peptide

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d1l2ia_:

Sequence, based on SEQRES records:

>d1l2ia_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml
dah

Sequence, based on observed residues (ATOM records):

>d1l2ia_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvyleekdhihrvldkitdtlihlmaka
gltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemldah

Timeline for d1l2ia_:

• d1l2ia_ first appeared in SCOP 1.61
  
• d1l2ia_ appears in SCOPe 2.06
  
• d1l2ia_ appears in the current release, SCOPe 2.08