SCOP 1.65: Domain d1kvka2: 1kvk A:226-394

Lineage for d1kvka2 (1kvk A:226-394)

1. Root: SCOP 1.65

2. Class d: Alpha and beta proteins (a+b) [53931] (234 folds)

3. Fold d.58: Ferredoxin-like [54861] (48 superfamilies)
   alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2

4. Superfamily d.58.26: GHMP Kinase, C-terminal domain [55060] (6 families)
   common fold is elaborated with additional secondary structures

5. Family d.58.26.3: Mevalonate kinase [75450] (1 protein)

6. Protein Mevalonate kinase [75451] (2 species)

7. Species Rat (Rattus norvegicus) [TaxId:10116] [75453] (1 PDB entry)

8. Domain d1kvka2: 1kvk A:226-394 [73061]
   Other proteins in same PDB: d1kvka1
   complexed with atp, mg

Details for d1kvka2

PDB Entry: 1kvk, 2.4 Å

PDB Description: the structure of binary complex between a mammalian mevalonate kinase and atp: insights into the reaction mechanism and human inherited disease

SCOP Domain Sequences for d1kvka2:

Sequence; same for both SEQRES and ATOM records:

>d1kvka2 d.58.26.3 (A:226-394) Mevalonate kinase {Rat (Rattus norvegicus)}
rlpalqilltntkvprstkalvagvrsrlikfpeimaplltsidaislecervlgemaaa
pvpeqylvleelmdmnqhhlnalgvghasldqlcqvtaahglhskltgaggggcgitllk
pglerakveaakqaltgcgfdcwetsigapgvsmhsatsiedpvrqalg

Timeline for d1kvka2:

• d1kvka2 first appeared in SCOP 1.61
  
• d1kvka2 appears in SCOP 1.63
  
• d1kvka2 appears in SCOP 1.67
  
• d1kvka2 appears in the current release, SCOPe 2.08