SCOP 1.69: Domain d1ki1b1: 1ki1 B:1229-1438

Lineage for d1ki1b1 (1ki1 B:1229-1438)

1. Root: SCOP 1.69

2. Class a: All alpha proteins [46456] (218 folds)

3. Fold a.87: DBL homology domain (DH-domain) [48064] (1 superfamily)
   multihelical; core: 5-helical bundle

4. Superfamily a.87.1: DBL homology domain (DH-domain) [48065] (1 family)

5. Family a.87.1.1: DBL homology domain (DH-domain) [48066] (8 proteins)
   Pfam 00621

6. Protein GEF of intersectin [74745] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [74746] (1 PDB entry)

8. Domain d1ki1b1: 1ki1 B:1229-1438 [72497]
   Other proteins in same PDB: d1ki1a_, d1ki1b2, d1ki1c_, d1ki1d2

Details for d1ki1b1

PDB Entry: 1ki1, 2.3 Å

PDB Description: guanine nucleotide exchange region of intersectin in complex with cdc42

SCOP Domain Sequences for d1ki1b1:

Sequence; same for both SEQRES and ATOM records:

>d1ki1b1 a.87.1.1 (B:1229-1438) GEF of intersectin {Human (Homo sapiens)}
dmltpterkrqgyihelivteenyvndlqlvteifqkplmeselltekevamifvnwkel
imcnikllkalrvrkkmsgekmpvkmigdilsaqlphmqpyirfcsrqlngaaliqqktd
eapdfkefvkrlemdprckgmplssfilkpmqrvtrypliiknilentpenhpdhshlkh
alekaeelcsqvnegvrekensdrlewiqa

Timeline for d1ki1b1:

• d1ki1b1 first appeared in SCOP 1.61
  
• d1ki1b1 appears in SCOP 1.67
  
• d1ki1b1 appears in SCOP 1.71
  
• d1ki1b1 appears in the current release, SCOPe 2.08