SCOPe 2.06: Domain d1kc2a_: 1kc2 A:

Lineage for d1kc2a_ (1kc2 A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein c-src tyrosine kinase [55556] (3 species)

7. Species Rous sarcoma virus [TaxId:11886] [69782] (12 PDB entries)

8. Domain d1kc2a_: 1kc2 A: [72291]
   complexed with co; mutant

Details for d1kc2a_

PDB Entry: 1kc2, 2.1 Å

PDB Description: structure of the triple (lys(beta)d3ala, asp(beta)c8ala, aspcd2ala) mutant of the src sh2 domain bound to the pqpyeeipi peptide

PDB Compounds: (A:) Src Tyrosine kinase

SCOPe Domain Sequences for d1kc2a_:

Sequence, based on SEQRES records:

>d1kc2a_ d.93.1.1 (A:) c-src tyrosine kinase {Rous sarcoma virus [TaxId: 11886]}
aeewyfgkitrreserlllnpenprgtflvresettkgayclsvsafanakglnvahyki
rkldsggfyitsrtqfsslqqlvayyskhadglchrltnvcpt

Sequence, based on observed residues (ATOM records):

>d1kc2a_ d.93.1.1 (A:) c-src tyrosine kinase {Rous sarcoma virus [TaxId: 11886]}
aeewyfgkitrreserlllnpenprgtflvresettkgayclsvslnvahykirkldsgg
fyitsrtqfsslqqlvayyskhadglchrltnvcpt

Timeline for d1kc2a_:

• d1kc2a_ first appeared in SCOP 1.61
  
• d1kc2a_ appears in SCOPe 2.05
  
• d1kc2a_ appears in SCOPe 2.07
  
• d1kc2a_ appears in the current release, SCOPe 2.08