SCOP 1.71: Domain d1k3tb2: 1k3t B:165-333

Lineage for d1k3tb2 (1k3t B:165-333)

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.81: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55346] (1 superfamily)
   core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1

4. Superfamily d.81.1: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain [55347] (5 families)
   N-terminal domain is the classic Rossmann-fold

5. Family d.81.1.1: GAPDH-like [55348] (4 proteins)
   has many additional secondary structures

6. Protein Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [55349] (16 species)

7. Species Trypanosoma cruzi [TaxId:5693] [75483] (3 PDB entries)

8. Domain d1k3tb2: 1k3t B:165-333 [72025]
   Other proteins in same PDB: d1k3ta1, d1k3tb1, d1k3tc1, d1k3td1

Details for d1k3tb2

PDB Entry: 1k3t, 1.95 Å

PDB Description: Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi Complexed with Chalepin, a Coumarin Derivative Inhibitor

SCOP Domain Sequences for d1k3tb2:

Sequence; same for both SEQRES and ATOM records:

>d1k3tb2 d.81.1.1 (B:165-333) Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) {Trypanosoma cruzi}
scttnclapivhvlvkegfgvqtglmttihsytatqktvdgvsvkdwrggraaavniips
ttgaakavgmvipstqgkltgmsfrvptpdvsvvdltftaardtsiqeidaalkraskty
mkgilgytdeelvsadfindnrssiydskatlqnnlpkerrffkivswy

Timeline for d1k3tb2:

• d1k3tb2 first appeared in SCOP 1.61
  
• d1k3tb2 appears in SCOP 1.69
  
• d1k3tb2 appears in SCOP 1.73
  
• d1k3tb2 appears in the current release, SCOPe 2.08