SCOPe 2.06: Domain d1jyqa1: 1jyq A:60-151

Lineage for d1jyqa1 (1jyq A:60-151)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55564] (35 PDB entries)

8. Domain d1jyqa1: 1jyq A:60-151 [71967]
   Other proteins in same PDB: d1jyqa2, d1jyqb2

Details for d1jyqa1

PDB Entry: 1jyq, 2 Å

PDB Description: xray structure of grb2 sh2 domain complexed with a highly affine phospho peptide

PDB Compounds: (A:) Growth factor receptor-bound protein 2

SCOPe Domain Sequences for d1jyqa1:

Sequence; same for both SEQRES and ATOM records:

>d1jyqa1 d.93.1.1 (A:60-151) Growth factor receptor-bound protein 2 (GRB2) {Human (Homo sapiens) [TaxId: 9606]}
wffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdgagkyf
lwvvkfnslnelvdyhrstsvsrnqqiflrdi

Timeline for d1jyqa1:

• d1jyqa1 first appeared in SCOP 1.61, called d1jyqa_
  
• d1jyqa1 was called d1jyqa_ in SCOPe 2.05
  
• d1jyqa1 appears in SCOPe 2.07
  
• d1jyqa1 appears in the current release, SCOPe 2.08