Lineage for d1jvka1 (1jvk A:1-112)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2019185Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2019217Species Human (Homo sapiens), cluster 4 [TaxId:9606] [88539] (23 PDB entries)
  8. 2019218Domain d1jvka1: 1jvk A:1-112 [71897]
    Other proteins in same PDB: d1jvka2, d1jvkb2
    part of amyloidogenic protein BUR

Details for d1jvka1

PDB Entry: 1jvk (more details), 1.94 Å

PDB Description: three-dimensional structure of an immunoglobulin light chain dimer acting as a lethal amyloid precursor
PDB Compounds: (A:) immunoglobulin lambda light chain

SCOPe Domain Sequences for d1jvka1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1jvka1 b.1.1.1 (A:1-112) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 4 [TaxId: 9606]}

SCOPe Domain Coordinates for d1jvka1:

Click to download the PDB-style file with coordinates for d1jvka1.
(The format of our PDB-style files is described here.)

Timeline for d1jvka1:

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