SCOPe 2.01: Domain d1j96b_: 1j96 B:

Lineage for d1j96b_ (1j96 B:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein 3-alpha-hydroxysteroid dehydrogenase [51439] (2 species)

7. Species Human (Homo sapiens), type III [TaxId:9606] [69383] (5 PDB entries)
   bile acid binding protein

8. Domain d1j96b_: 1j96 B: [71617]
   complexed with act, nap, tes

Details for d1j96b_

PDB Entry: 1j96, 1.25 Å

PDB Description: Human 3alpha-HSD type 3 in Ternary Complex with NADP and Testosterone

PDB Compounds: (B:) 3alpha-hydroxysteroid dehydrogenase type 3

SCOPe Domain Sequences for d1j96b_:

Sequence, based on SEQRES records:

>d1j96b_ c.1.7.1 (B:) 3-alpha-hydroxysteroid dehydrogenase {Human (Homo sapiens), type III [TaxId: 9606]}
ddskyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynneeq
vglairskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihfpv
svkpgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemilnkp
glkykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpv
lcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidgln
rnvryltldifagppnypfsdey

Sequence, based on observed residues (ATOM records):

>d1j96b_ c.1.7.1 (B:) 3-alpha-hydroxysteroid dehydrogenase {Human (Homo sapiens), type III [TaxId: 9606]}
ddskyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynneeq
vglairskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihfpv
svkpgeevipkilfdtvdlcatweamekckdaglaksigvsnfnhrllemilnkpglkyk
pvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpvlcala
kkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidglnrnvry
ltldifagppnypfsdey

Timeline for d1j96b_:

• d1j96b_ first appeared in SCOP 1.61
  
• d1j96b_ appears in SCOP 1.75
  
• d1j96b_ appears in SCOPe 2.02
  
• d1j96b_ appears in the current release, SCOPe 2.08, called d1j96b1