SCOPe 2.02: Domain d1j96a_: 1j96 A:

Lineage for d1j96a_ (1j96 A:)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein 3-alpha-hydroxysteroid dehydrogenase [51439] (2 species)

7. Species Human (Homo sapiens), type III [TaxId:9606] [69383] (5 PDB entries)
   bile acid binding protein

8. Domain d1j96a_: 1j96 A: [71616]
   complexed with act, nap, tes

Details for d1j96a_

PDB Entry: 1j96, 1.25 Å

PDB Description: Human 3alpha-HSD type 3 in Ternary Complex with NADP and Testosterone

PDB Compounds: (A:) 3alpha-hydroxysteroid dehydrogenase type 3

SCOPe Domain Sequences for d1j96a_:

Sequence; same for both SEQRES and ATOM records:

>d1j96a_ c.1.7.1 (A:) 3-alpha-hydroxysteroid dehydrogenase {Human (Homo sapiens), type III [TaxId: 9606]}
ddskyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynneeq
vglairskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihfpv
svkpgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemilnkp
glkykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpv
lcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidgln
rnvryltldifagppnypfsdey

Timeline for d1j96a_:

• d1j96a_ first appeared in SCOP 1.61
  
• d1j96a_ appears in SCOPe 2.01
  
• d1j96a_ appears in SCOPe 2.03
  
• d1j96a_ appears in the current release, SCOPe 2.08, called d1j96a1