SCOPe 2.08: Domain d1issa_: 1iss A:

Lineage for d1issa_ (1iss A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.93: Periplasmic binding protein-like I [53821] (1 superfamily)
   consists of two similar intertwined domain with 3 layers (a/b/a) each: duplication
   parallel beta-sheet of 6 strands, order 213456

4. Superfamily c.93.1: Periplasmic binding protein-like I [53822] (2 families)
   Similar in architecture to the superfamily II but partly differs in topology

5. Family c.93.1.1: L-arabinose binding protein-like [53823] (18 proteins)
   has additional insertions and/or extensions that are not grouped together
   

6. Protein Metabotropic glutamate receptor subtype 1 [53847] (1 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [53848] (5 PDB entries)

8. Domain d1issa_: 1iss A: [71404]
   complexed with mcg
   has additional insertions and/or extensions that are not grouped together

Details for d1issa_

PDB Entry: 1iss, 3.3 Å

PDB Description: Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with an antagonist

PDB Compounds: (A:) metabotropic glutamate receptor subtype 1

SCOPe Domain Sequences for d1issa_:

Sequence, based on SEQRES records:

>d1issa_ c.93.1.1 (A:) Metabotropic glutamate receptor subtype 1 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
rsvarmdgdviigalfsvhhqppaekvperkcgeireqygiqrveamfhtldkinadpvl
lpnitlgseirdscwhssvaleqsiefirdslisirdekdglnrclpdgqtlppgrtkkp
iagvigpgsssvaiqvqnllqlfdipqiaysatsidlsdktlykyflrvvpsdtlqaram
ldivkrynwtyvsavhtegnygesgmdafkelaaqeglciahsdkiysnageksfdrllr
klrerlpkarvvvcfcegmtvrgllsamrrlgvvgefsligsdgwadrdeviegyevean
ggitiklqspevrsfddyflklrldtntrnpwfpefwqhrfqcrlpghllenpnfkkvct
gnesleenyvqdskmgfvinaiyamahglqnmhhalcpghvglcdamkpidgrklldfli
kssfvgvsgeevwfdekgdapgrydimnlqyteanrydyvhvgtwhegvlniddyki

Sequence, based on observed residues (ATOM records):

>d1issa_ c.93.1.1 (A:) Metabotropic glutamate receptor subtype 1 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
rsvarmdgdviigalfsvhhqppaekvperkcgeireqygiqrveamfhtldkinadpvl
lpnitlgseirdscwhssvaleqsiefirdslikpiagvigpgsssvaiqvqnllqlfdi
pqiaysatsidlsdktlykyflrvvpsdtlqaramldivkrynwtyvsavhtegnygesg
mdafkelaaqeglciahsdkiysnageksfdrllrklrerlpkarvvvcfcegmtvrgll
samrrlgvvgefsligsdgwadrdeviegyeveanggitiklqspevrsfddyflklrld
tntrnpwfpefwqhrfqcrlpghllenpnfkkvctgnesleenyvqdskmgfvinaiyam
ahglqnmhhalcpghvglcdamkpidgrklldflikssfvgvsgeevwfdekgdapgryd
imnlqyteanrydyvhvgtwhegvlniddyki

Timeline for d1issa_:

• d1issa_ first appeared in SCOP 1.61
  
• d1issa_ appears in SCOPe 2.07