SCOPe 2.05: Domain d1irid_: 1iri D:

Lineage for d1irid_ (1iri D:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.80: SIS domain [53696] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 5 strands, order 21345

4. Superfamily c.80.1: SIS domain [53697] (4 families)

5. Family c.80.1.2: Phosphoglucose isomerase, PGI [53701] (2 proteins)
   permutation of the double-SIS domain fold
   automatically mapped to Pfam PF00342

6. Protein Phosphoglucose isomerase, PGI [53702] (7 species)
   moonlights as neuroleukin, autocrine motility factor, and differentiation mediator

7. Species Human (Homo sapiens) [TaxId:9606] [64176] (5 PDB entries)

8. Domain d1irid_: 1iri D: [71346]
   complexed with e4p

Details for d1irid_

PDB Entry: 1iri, 2.4 Å

PDB Description: Crystal structure of human autocrine motility factor complexed with an inhibitor

PDB Compounds: (D:) autocrine motility factor

SCOPe Domain Sequences for d1irid_:

Sequence; same for both SEQRES and ATOM records:

>d1irid_ c.80.1.2 (D:) Phosphoglucose isomerase, PGI {Human (Homo sapiens) [TaxId: 9606]}
maaltrdpqfqklqqwyrehrselnlrrlfdankdrfnhfsltlntnhghilvdysknlv
tedvmrmlvdlaksrgveaarermfngekinytegravlhvalrnrsntpilvdgkdvmp
evnkvldkmksfcqrvrsgdwkgytgktitdvinigiggsdlgplmvtealkpyssggpr
vwyvsnidgthiaktlaqlnpesslfiiasktfttqetitnaetakewflqaakdpsava
khfvalstnttkvkefgidpqnmfefwdwvggryslwsaiglsialhvgfdnfeqllsga
hwmdqhfrttpleknapvllallgiwyincfgcethamlpydqylhrfaayfqqgdmesn
gkyitksgtrvdhqtgpivwgepgtngqhafyqlihqgtkmipcdflipvqtqhpirkgl
hhkillanflaqtealmrgksteearkelqaagkspedlerllphkvfegnrptnsivft
kltpfmlgalvamyehkifvqgiiwdinsfdqwgvelgkqlakkiepeldgsaqvtshda
stnglinfikqqrearv

Timeline for d1irid_:

• d1irid_ first appeared in SCOP 1.61
  
• d1irid_ appears in SCOPe 2.04
  
• d1irid_ appears in SCOPe 2.06
  
• d1irid_ appears in the current release, SCOPe 2.08