SCOPe 2.04: Domain d1i9il1: 1i9i L:1-112

Lineage for d1i9il1 (1i9i L:1-112)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (131 PDB entries)
   Uniprot P01631 #KV2G_MOUSE Ig kappa chain V-II region 26-10; 79% sequence identity ! Uniprot P06310 # KV2F_HUMAN IG KAPPA CHAIN V-II REGION RPMI 6410 PRECURSOR ! Uniprot P03976 # KV2E_MOUSE (P03976) Ig kappa chain V-II region 17S29.1 ! Uniprot P01642 21-115 # ! KV2G_MOUSE IG KAPPA CHAIN V-II REGION 26-10

8. Domain d1i9il1: 1i9i L:1-112 [71142]
   Other proteins in same PDB: d1i9ih1, d1i9ih2, d1i9il2
   part of anti-testosterone Fab

Details for d1i9il1

PDB Entry: 1i9i, 2.72 Å

PDB Description: native crystal structure of the recombinant monoclonal wild type anti-testosterone fab fragment

PDB Compounds: (L:) recombinant monoclonal anti-testosterone fab fragment light chain

SCOPe Domain Sequences for d1i9il1:

Sequence; same for both SEQRES and ATOM records:

>d1i9il1 b.1.1.1 (L:1-112) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1 [TaxId: 10090]}
dvvvtqtplslpvslgdqasiscrssqsivhsngnsylewylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyycfqgshvpptfgggtkleik

Timeline for d1i9il1:

• d1i9il1 first appeared in SCOP 1.61
  
• d1i9il1 appears in SCOPe 2.03
  
• d1i9il1 appears in SCOPe 2.05
  
• d1i9il1 appears in the current release, SCOPe 2.08