SCOPe 2.06: Domain d1hy3a_: 1hy3 A:

Lineage for d1hy3a_ (1hy3 A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.5: PAPS sulfotransferase [52575] (15 proteins)
   Pfam PF00685
   similar to the nucleotide/nucleoside kinases but transfer sulphate group

6. Protein Estrogen sulfotransferase (STE, sult1e1) [52576] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [75198] (5 PDB entries)

8. Domain d1hy3a_: 1hy3 A: [71090]
   complexed with pps; mutant

Details for d1hy3a_

PDB Entry: 1hy3, 1.8 Å

PDB Description: crystal structure of human estrogen sulfotransferase v269e mutant in the presence of paps

PDB Compounds: (A:) estrogen sulfotransferase

SCOPe Domain Sequences for d1hy3a_:

Sequence, based on SEQRES records:

>d1hy3a_ c.37.1.5 (A:) Estrogen sulfotransferase (STE, sult1e1) {Human (Homo sapiens) [TaxId: 9606]}
nseldyyekfeevhgilmykdfvkywdnveafqarpddlviatypksgttwvseivymiy
kegdvekckedvifnripflecrkenlmngvkqldemnsprivkthlppellpasfwekd
ckiiylcrnakdvavsfyyfflmvaghpnpgsfpefvekfmqgqvpygswykhvkswwek
gksprvlflfyedlkedirkeviklihflerkpseelvdriihhtsfqemknnpstnytt
lpdeimnqklspfmrkgitgdwknhftealnekfdkhyeqqmkestlkf

Sequence, based on observed residues (ATOM records):

>d1hy3a_ c.37.1.5 (A:) Estrogen sulfotransferase (STE, sult1e1) {Human (Homo sapiens) [TaxId: 9606]}
nseldyyekfeevhgilmykdfvkywdnveafqarpddlviatypksgttwvseivymiy
kegdvekckedvifnripflecrkenlmngvkqldemnsprivkthlppellpasfwekd
ckiiylcrnakdvavsfyyfflmvaghpnpgsfpefvekfmqgqvpygswykhvkswwek
gksprvlflfyedlkedirkeviklihflerkpseelvdriihhtsfqemknnpstnytt
lpdeimnqkpfmrkgitgdwknhftealnekfdkhyeqqmkestlkf

Timeline for d1hy3a_:

• d1hy3a_ first appeared in SCOP 1.61
  
• d1hy3a_ appears in SCOPe 2.05
  
• d1hy3a_ appears in SCOPe 2.07
  
• d1hy3a_ appears in the current release, SCOPe 2.08