SCOP 1.67: Domain d1gzgb_: 1gzg B:

Lineage for d1gzgb_ (1gzg B:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (28 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (5 families)
   Common fold covers whole protein structure

5. Family c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (1 protein)
   hybrid of classes I and II aldolase

6. Protein 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51595] (4 species)

7. Species Pseudomonas aeruginosa [TaxId:287] [51597] (2 PDB entries)

8. Domain d1gzgb_: 1gzg B: [70806]
   complexed with k, laf, mg, na, so4; mutant

Details for d1gzgb_

PDB Entry: 1gzg, 1.66 Å

PDB Description: complex of a mg2-dependent porphobilinogen synthase from pseudomonas aeruginosa (mutant d139n) with 5-fluorolevulinic acid

SCOP Domain Sequences for d1gzgb_:

Sequence, based on SEQRES records:

>d1gzgb_ c.1.10.3 (B:) 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) {Pseudomonas aeruginosa}
panraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgverls
idqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpelgi
itdvaldpftthgqngildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgriga
irealesaghtnvrvmaysakyasayygpfrdavgsasnlgkgnkatyqmdpansdealh
evaadlaegadmvmvkpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngwlaes
vilesltafkragadgiltyfakqaaeqlrr

Sequence, based on observed residues (ATOM records):

>d1gzgb_ c.1.10.3 (B:) 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) {Pseudomonas aeruginosa}
panraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgverls
idqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpelgi
itdvaldpftthgqngildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgriga
irealesaghtnvrvmaysakyasayygpfrdavgskatyqmdpansdealhevaadlae
gadmvmvkpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngwlaesvileslta
fkragadgiltyfakqaaeqlrr

Timeline for d1gzgb_:

• d1gzgb_ first appeared in SCOP 1.61
  
• d1gzgb_ appears in SCOP 1.65
  
• d1gzgb_ appears in SCOP 1.69
  
• d1gzgb_ appears in the current release, SCOPe 2.08