SCOPe 2.05: Domain d1gy3a_: 1gy3 A:

Lineage for d1gy3a_ (1gy3 A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (348 PDB entries)
   Uniprot P24941

8. Domain d1gy3a_: 1gy3 A: [70728]
   Other proteins in same PDB: d1gy3b1, d1gy3b2, d1gy3d1, d1gy3d2
   complexed with atp, gol, mg, no3

Details for d1gy3a_

PDB Entry: 1gy3, 2.7 Å

PDB Description: pcdk2/cyclin a in complex with mgadp, nitrate and peptide substrate

PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d1gy3a_:

Sequence; same for both SEQRES and ATOM records:

>d1gy3a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Timeline for d1gy3a_:

• d1gy3a_ first appeared in SCOP 1.61
  
• d1gy3a_ appears in SCOPe 2.04
  
• d1gy3a_ appears in SCOPe 2.06
  
• d1gy3a_ appears in the current release, SCOPe 2.08