SCOP 1.69: Domain d1gv4a1: 1gv4 A:121-264,A:398-477

Lineage for d1gv4a1 (1gv4 A:121-264,A:398-477)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (5 families)

5. Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (13 proteins)
   duplication: both domains have similar folds and functions
   most members of the family contain common C-terminal alpha+beta domain

6. Protein Apoptosis-inducing factor (AIF) [75126] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [75128] (1 PDB entry)

8. Domain d1gv4a1: 1gv4 A:121-264,A:398-477 [70589]
   Other proteins in same PDB: d1gv4a3, d1gv4b3

Details for d1gv4a1

PDB Entry: 1gv4, 2 Å

PDB Description: murine apoptosis-inducing factor (aif)

SCOP Domain Sequences for d1gv4a1:

Sequence; same for both SEQRES and ATOM records:

>d1gv4a1 c.3.1.5 (A:121-264,A:398-477) Apoptosis-inducing factor (AIF) {Mouse (Mus musculus)}
tvpqirapshvpflligggtaafaaarsirardpgarvlivsedpelpymrpplskelwf
sddpnvtktlqfrqwngkersiyfqppsfyvsaqdlpnienggvavltgkkvvhldvrgn
mvklndgsqitfekcliatggtprXglepnvelaktggleidsdfggfrvnaelqarsni
wvagdaacfydiklgrrrvehhdhavvsgrlagenmtgaakpywh

Timeline for d1gv4a1:

• d1gv4a1 first appeared in SCOP 1.61
  
• d1gv4a1 appears in SCOP 1.67
  
• d1gv4a1 appears in SCOP 1.71
  
• d1gv4a1 appears in the current release, SCOPe 2.08