SCOPe 2.08: Domain d1gr0a1: 1gr0 A:14-200,A:312-367

Lineage for d1gr0a1 (1gr0 A:14-200,A:312-367)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

6. Protein Myo-inositol 1-phosphate synthase [75105] (4 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [75106] (1 PDB entry)

8. Domain d1gr0a1: 1gr0 A:14-200,A:312-367 [70379]
   Other proteins in same PDB: d1gr0a2
   complexed with cac, nad, zn
   has additional insertions and/or extensions that are not grouped together

Details for d1gr0a1

PDB Entry: 1gr0, 1.95 Å

PDB Description: myo-inositol 1-phosphate synthase from mycobacterium tuberculosis in complex with nad and zinc.

PDB Compounds: (A:) Inositol-3-phosphate synthase

SCOPe Domain Sequences for d1gr0a1:

Sequence; same for both SEQRES and ATOM records:

>d1gr0a1 c.2.1.3 (A:14-200,A:312-367) Myo-inositol 1-phosphate synthase {Mycobacterium tuberculosis [TaxId: 1773]}
tevrvaivgvgncasslvqgveyyynaddtstvpglmhvrfgpyhvrdvkfvaafdvdak
kvgfdlsdaifasenntikiadvaptnvivqrgptldgigkyyadtielsdaepvdvvqa
lkeakvdvlvsylpvgseeadkfyaqcaidagvafvnalpvfiasdpvwakkftdarvpi
vgddiksXpnsagviidavraakiakdrgiggpvipasaylmksppeqlpddiaraqlee
fiig

Timeline for d1gr0a1:

• d1gr0a1 first appeared in SCOP 1.61
  
• d1gr0a1 appears in SCOPe 2.07