SCOP 1.65: Domain d1gjoa_: 1gjo A:

Lineage for d1gjoa_ (1gjo A:)

1. Root: SCOP 1.65

2. Class d: Alpha and beta proteins (a+b) [53931] (234 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (41 proteins)
   members organised in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 2 [75562] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [75563] (1 PDB entry)

8. Domain d1gjoa_: 1gjo A: [70192]
   complexed with so4

Details for d1gjoa_

PDB Entry: 1gjo, 2.4 Å

PDB Description: the fgfr2 tyrosine kinase domain

SCOP Domain Sequences for d1gjoa_:

Sequence, based on SEQRES records:

>d1gjoa_ d.144.1.7 (A:) Fibroblast growth factor receptor 2 {Human (Homo sapiens)}
elpedpkwefprdkltlgkplgegcfgqvvmaeavgidkdkpkeavtvavkmlkddatek
dlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrppgmey
sydinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfg
lardinnidyykkttngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypg
ipveelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlt

Sequence, based on observed residues (ATOM records):

>d1gjoa_ d.144.1.7 (A:) Fibroblast growth factor receptor 2 {Human (Homo sapiens)}
elpedpkwefprdkltlgkplgegcfgqvvmaeavgikpkeavtvavkmlkddatekdls
dlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarreqmtfkdlv
sctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglardinnidyykkttngr
lpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgipveelfkllkeghrmdk
panctnelymmmrdcwhavpsqrptfkqlvedldriltlt

Timeline for d1gjoa_:

• d1gjoa_ first appeared in SCOP 1.61
  
• d1gjoa_ appears in SCOP 1.63
  
• d1gjoa_ appears in SCOP 1.67
  
• d1gjoa_ appears in the current release, SCOPe 2.08