Lineage for Protein: Tyrosyl-DNA phosphodiesterase TDP1

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2540800Fold d.136: Phospholipase D/nuclease [56023] (1 superfamily)
    beta-alpha-beta-alpha-beta-alpha-beta(4)-alpha; mixed sheet: order 1765234
  4. 2540801Superfamily d.136.1: Phospholipase D/nuclease [56024] (6 families) (S)
  5. 2540826Family d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1 [69815] (2 proteins)
  6. 2540827Protein Tyrosyl-DNA phosphodiesterase TDP1 [69816] (2 species)

Species:

  1. 2540828Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [111180] (1 PDB entry)
    Uniprot P38319 79-538
  2. 2540837Human (Homo sapiens) [TaxId:9606] [69817] (36 PDB entries)
    1. Domains for 1jy1:
      1. 2540838Domain d1jy1a1: 1jy1 A:149-350 [67438]
        Other proteins in same PDB: d1jy1a3
      2. 2540839Domain d1jy1a2: 1jy1 A:351-608 [67439]
        Other proteins in same PDB: d1jy1a3
    2. Domains for 1mu7:
      1. 2540844Domain d1mu7a1: 1mu7 A:162-350 [79475]
        protein/DNA complex; complexed with gol, wo4
      2. 2540845Domain d1mu7a2: 1mu7 A:351-608 [79476]
        protein/DNA complex; complexed with gol, wo4
      3. 2540846Domain d1mu7b1: 1mu7 B:158-350 [79477]
        protein/DNA complex; complexed with gol, wo4
      4. 2540847Domain d1mu7b2: 1mu7 B:351-608 [79478]
        protein/DNA complex; complexed with gol, wo4
    3. Domains for 1mu9:
      1. 2540852Domain d1mu9a1: 1mu9 A:162-350 [79479]
        protein/DNA complex; complexed with gol, vo4
      2. 2540853Domain d1mu9a2: 1mu9 A:351-608 [79480]
        protein/DNA complex; complexed with gol, vo4
      3. 2540854Domain d1mu9b1: 1mu9 B:159-350 [79481]
        protein/DNA complex; complexed with gol, vo4
      4. 2540855Domain d1mu9b2: 1mu9 B:351-608 [79482]
        protein/DNA complex; complexed with gol, vo4
    4. Domains for 1nop:
      1. 2540876Domain d1nopa1: 1nop A:162-350 [85928]
        complexed with a topoisomerase I-derived peptide, chain C
        protein/DNA complex; complexed with vo4
      2. 2540877Domain d1nopa2: 1nop A:351-608 [85929]
        complexed with a topoisomerase I-derived peptide, chain C
        protein/DNA complex; complexed with vo4
      3. 2540878Domain d1nopb1: 1nop B:159-350 [85930]
        complexed with a topoisomerase I-derived peptide, chain C
        protein/DNA complex; complexed with vo4
      4. 2540879Domain d1nopb2: 1nop B:351-607 [85931]
        complexed with a topoisomerase I-derived peptide, chain C
        protein/DNA complex; complexed with vo4
    5. Domains for 1qzq:
      1. 2540880Domain d1qzqa1: 1qzq A:161-350 [96655]
      2. 2540881Domain d1qzqa2: 1qzq A:351-608 [96656]
      3. 2540882Domain d1qzqb1: 1qzq B:161-350 [96657]
      4. 2540883Domain d1qzqb2: 1qzq B:351-608 [96658]
    6. Domains for 1rff:
      1. 2540840Domain d1rffa1: 1rff A:162-350 [97376]
        protein/DNA complex; complexed with spm, vo4
      2. 2540841Domain d1rffa2: 1rff A:351-608 [97377]
        protein/DNA complex; complexed with spm, vo4
      3. 2540842Domain d1rffb1: 1rff B:162-350 [97378]
        protein/DNA complex; complexed with spm, vo4
      4. 2540843Domain d1rffb2: 1rff B:351-607 [97379]
        protein/DNA complex; complexed with spm, vo4
    7. Domains for 1rfi:
      1. 2540864Domain d1rfia1: 1rfi A:162-350 [97380]
        protein/DNA complex; complexed with spm, vo4
      2. 2540865Domain d1rfia2: 1rfi A:351-608 [97381]
        protein/DNA complex; complexed with spm, vo4
      3. 2540866Domain d1rfib1: 1rfi B:162-350 [97382]
        protein/DNA complex; complexed with spm, vo4
      4. 2540867Domain d1rfib2: 1rfi B:351-607 [97383]
        protein/DNA complex; complexed with spm, vo4
    8. Domains for 1rg1:
      1. 2540860Domain d1rg1a1: 1rg1 A:162-350 [97415]
        protein/DNA complex; complexed with ots, spm, vo4
      2. 2540861Domain d1rg1a2: 1rg1 A:351-608 [97416]
        protein/DNA complex; complexed with ots, spm, vo4
      3. 2540862Domain d1rg1b1: 1rg1 B:162-350 [97417]
        protein/DNA complex; complexed with ots, spm, vo4
      4. 2540863Domain d1rg1b2: 1rg1 B:351-607 [97418]
        protein/DNA complex; complexed with ots, spm, vo4
    9. Domains for 1rg2:
      1. 2540856Domain d1rg2a1: 1rg2 A:162-350 [97419]
        protein/DNA complex; complexed with otr, ots, spm, vo4
      2. 2540857Domain d1rg2a2: 1rg2 A:351-608 [97420]
        protein/DNA complex; complexed with otr, ots, spm, vo4
      3. 2540858Domain d1rg2b1: 1rg2 B:159-350 [97421]
        protein/DNA complex; complexed with otr, ots, spm, vo4
      4. 2540859Domain d1rg2b2: 1rg2 B:351-608 [97422]
        protein/DNA complex; complexed with otr, ots, spm, vo4
    10. Domains for 1rgt:
      1. 2540848Domain d1rgta1: 1rgt A:162-350 [97446]
        protein/DNA complex; complexed with otr, ots, spm, vo4
      2. 2540849Domain d1rgta2: 1rgt A:351-608 [97447]
        protein/DNA complex; complexed with otr, ots, spm, vo4
      3. 2540850Domain d1rgtb1: 1rgt B:162-350 [97448]
        protein/DNA complex; complexed with otr, ots, spm, vo4
      4. 2540851Domain d1rgtb2: 1rgt B:351-607 [97449]
        protein/DNA complex; complexed with otr, ots, spm, vo4
    11. Domains for 1rgu:
      1. 2540868Domain d1rgua1: 1rgu A:162-350 [97450]
        protein/DNA complex; complexed with ots, spm, vo4
      2. 2540869Domain d1rgua2: 1rgu A:351-608 [97451]
        protein/DNA complex; complexed with ots, spm, vo4
      3. 2540870Domain d1rgub1: 1rgu B:162-350 [97452]
        protein/DNA complex; complexed with ots, spm, vo4
      4. 2540871Domain d1rgub2: 1rgu B:351-607 [97453]
        protein/DNA complex; complexed with ots, spm, vo4
    12. Domains for 1rh0:
      1. 2540872Domain d1rh0a1: 1rh0 A:162-350 [97458]
        protein/DNA complex; complexed with ots, spm, vo4
      2. 2540873Domain d1rh0a2: 1rh0 A:351-608 [97459]
        protein/DNA complex; complexed with ots, spm, vo4
      3. 2540874Domain d1rh0b1: 1rh0 B:162-350 [97460]
        protein/DNA complex; complexed with ots, spm, vo4
      4. 2540875Domain d1rh0b2: 1rh0 B:351-607 [97461]
        protein/DNA complex; complexed with ots, spm, vo4
    13. Domains for 6dhu:
      1. 3069207Domain d6dhua1: 6dhu A:162-350 [369269]
        automated match to d1qzqa1
        complexed with edo, ghm
      2. 3069208Domain d6dhua2: 6dhu A:351-607 [369270]
        automated match to d1qzqa2
        complexed with edo, ghm
      3. 3069265Domain d6dhub1: 6dhu B:162-350 [369327]
        automated match to d1qzqa1
        complexed with edo, ghm
      4. 3069266Domain d6dhub2: 6dhu B:351-607 [369328]
        automated match to d1qzqa2
        complexed with edo, ghm
    14. Domains for 6die:
      1. 3069203Domain d6dieb1: 6die B:162-350 [369265]
        automated match to d1qzqa1
        complexed with edo, ghm
      2. 3069204Domain d6dieb2: 6die B:351-608 [369266]
        automated match to d1qzqa2
        complexed with edo, ghm
      3. 3069263Domain d6diea1: 6die A:162-350 [369325]
        automated match to d1qzqa1
        complexed with edo, ghm
      4. 3069264Domain d6diea2: 6die A:351-607 [369326]
        automated match to d1qzqa2
        complexed with edo, ghm
    15. Domains for 6dih:
      1. 3069201Domain d6dihb1: 6dih B:162-350 [369263]
        automated match to d1qzqa1
        complexed with edo, gjs
      2. 3069202Domain d6dihb2: 6dih B:351-607 [369264]
        automated match to d1qzqa2
        complexed with edo, gjs
      3. 3069325Domain d6diha1: 6dih A:162-350 [369387]
        automated match to d1qzqa1
        complexed with edo, gjs
      4. 3069326Domain d6diha2: 6dih A:351-607 [369388]
        automated match to d1qzqa2
        complexed with edo, gjs
    16. Domains for 6dim:
      1. 3069196Domain d6dimb1: 6dim B:162-350 [369258]
        automated match to d1qzqa1
        complexed with edo, gjp
      2. 3069197Domain d6dimb2: 6dim B:351-607 [369259]
        automated match to d1qzqa2
        complexed with edo, gjp
      3. 3069235Domain d6dima1: 6dim A:162-350 [369297]
        automated match to d1qzqa1
        complexed with edo, gjp
      4. 3069236Domain d6dima2: 6dim A:351-607 [369298]
        automated match to d1qzqa2
        complexed with edo, gjp
    17. Domains for 6djd:
      1. 3069205Domain d6djda1: 6djd A:162-350 [369267]
        automated match to d1qzqa1
        complexed with edo, gjp
      2. 3069206Domain d6djda2: 6djd A:351-607 [369268]
        automated match to d1qzqa2
        complexed with edo, gjp
      3. 3069380Domain d6djdb1: 6djd B:162-350 [369442]
        automated match to d1qzqa1
        complexed with edo, gjp
      4. 3069381Domain d6djdb2: 6djd B:351-607 [369443]
        automated match to d1qzqa2
        complexed with edo, gjp
    18. Domains for 6dje:
      1. 3069351Domain d6djea1: 6dje A:162-350 [369413]
        automated match to d1qzqa1
        complexed with edo, gny
      2. 3069352Domain d6djea2: 6dje A:351-607 [369414]
        automated match to d1qzqa2
        complexed with edo, gny
      3. 3069395Domain d6djeb1: 6dje B:162-350 [369457]
        automated match to d1qzqa1
        complexed with edo, gny
      4. 3069396Domain d6djeb2: 6dje B:351-607 [369458]
        automated match to d1qzqa2
        complexed with edo, gny
    19. Domains for 6djf:
      1. 3069195Domain d6djfb1: 6djf B:162-350 [369257]
        automated match to d1qzqa1
        complexed with edo, gnv
      2. 3069198Domain d6djfb2: 6djf B:351-607 [369260]
        automated match to d1qzqa2
        complexed with edo, gnv
      3. 3069241Domain d6djfa1: 6djf A:162-350 [369303]
        automated match to d1qzqa1
        complexed with edo, gnv
      4. 3069242Domain d6djfa2: 6djf A:351-607 [369304]
        automated match to d1qzqa2
        complexed with edo, gnv
    20. Domains for 6djg:
      1. 3069199Domain d6djga1: 6djg A:162-350 [369261]
        automated match to d1qzqa1
        complexed with edo, gnj
      2. 3069200Domain d6djga2: 6djg A:351-607 [369262]
        automated match to d1qzqa2
        complexed with edo, gnj
      3. 3069238Domain d6djgb1: 6djg B:162-350 [369300]
        automated match to d1qzqa1
        complexed with edo, gnj
      4. 3069239Domain d6djgb2: 6djg B:351-607 [369301]
        automated match to d1qzqa2
        complexed with edo, gnj
    21. Domains for 6djh:
      1. 3069393Domain d6djhb1: 6djh B:162-350 [369455]
        automated match to d1qzqa1
        complexed with edo, gnm
      2. 3069394Domain d6djhb2: 6djh B:351-607 [369456]
        automated match to d1qzqa2
        complexed with edo, gnm
      3. 3069397Domain d6djha1: 6djh A:162-350 [369459]
        automated match to d1qzqa1
        complexed with edo, gnm
      4. 3069398Domain d6djha2: 6djh A:351-607 [369460]
        automated match to d1qzqa2
        complexed with edo, gnm
    22. Domains for 6dji:
      1. 3069299Domain d6djib1: 6dji B:162-350 [369361]
        automated match to d1qzqa1
        complexed with edo, gog
      2. 3069300Domain d6djib2: 6dji B:351-607 [369362]
        automated match to d1qzqa2
        complexed with edo, gog
      3. 3069349Domain d6djia1: 6dji A:162-350 [369411]
        automated match to d1qzqa1
        complexed with edo, gog
      4. 3069350Domain d6djia2: 6dji A:351-607 [369412]
        automated match to d1qzqa2
        complexed with edo, gog
    23. Domains for 6djj:
      1. 3069302Domain d6djjb1: 6djj B:162-350 [369364]
        automated match to d1qzqa1
        complexed with edo, gm7
      2. 3069303Domain d6djjb2: 6djj B:351-607 [369365]
        automated match to d1qzqa2
        complexed with edo, gm7
      3. 3069377Domain d6djja1: 6djj A:162-350 [369439]
        automated match to d1qzqa1
        complexed with edo, gm7
      4. 3069378Domain d6djja2: 6djj A:351-607 [369440]
        automated match to d1qzqa2
        complexed with edo, gm7
    24. Domains for 6mj5:
      1. 3070551Domain d6mj5a1: 6mj5 A:162-350 [370613]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, jta
      2. 3070552Domain d6mj5a2: 6mj5 A:351-607 [370614]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, jta
      3. 3070566Domain d6mj5b1: 6mj5 B:162-350 [370628]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, jta
      4. 3070567Domain d6mj5b2: 6mj5 B:351-607 [370629]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, jta
    25. Domains for 6myz:
      1. 3076377Domain d6myza1: 6myz A:162-350 [376439]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k7d
      2. 3076378Domain d6myza2: 6myz A:351-607 [376440]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k7d
      3. 3076427Domain d6myzb1: 6myz B:162-350 [376489]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k7d
      4. 3076428Domain d6myzb2: 6myz B:351-607 [376490]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k7d
    26. Domains for 6mz0:
      1. 3076398Domain d6mz0a1: 6mz0 A:162-350 [376460]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k7a
      2. 3076399Domain d6mz0a2: 6mz0 A:351-607 [376461]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k7a
      3. 3076411Domain d6mz0b1: 6mz0 B:162-350 [376473]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k7a
      4. 3076412Domain d6mz0b2: 6mz0 B:351-607 [376474]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k7a
    27. Domains for 6n0d:
      1. 3076665Domain d6n0da1: 6n0d A:162-350 [376727]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k8j
      2. 3076666Domain d6n0da2: 6n0d A:351-607 [376728]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k8j
      3. 3076670Domain d6n0db1: 6n0d B:162-350 [376732]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k8j
      4. 3076671Domain d6n0db2: 6n0d B:351-607 [376733]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k8j
    28. Domains for 6n0n:
      1. 3076663Domain d6n0na1: 6n0n A:162-350 [376725]
        automated match to d1qzqa1
        protein/DNA complex; complexed with dms, edo, kay
      2. 3076664Domain d6n0na2: 6n0n A:351-607 [376726]
        automated match to d1qzqa2
        protein/DNA complex; complexed with dms, edo, kay
      3. 3076683Domain d6n0nb1: 6n0n B:162-350 [376745]
        automated match to d1qzqa1
        protein/DNA complex; complexed with dms, edo, kay
      4. 3076684Domain d6n0nb2: 6n0n B:351-607 [376746]
        automated match to d1qzqa2
        protein/DNA complex; complexed with dms, edo, kay
    29. Domains for 6n0o:
      1. 3076679Domain d6n0oa1: 6n0o A:162-350 [376741]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k8g
      2. 3076680Domain d6n0oa2: 6n0o A:351-607 [376742]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k8g
      3. 3076698Domain d6n0ob1: 6n0o B:162-350 [376760]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k8g
      4. 3076699Domain d6n0ob2: 6n0o B:351-607 [376761]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k8g
    30. Domains for 6n0r:
      1. 3076691Domain d6n0rb1: 6n0r B:162-350 [376753]
        automated match to d1qzqa1
        protein/DNA complex; complexed with dms, edo, k8d
      2. 3076692Domain d6n0rb2: 6n0r B:351-607 [376754]
        automated match to d1qzqa2
        protein/DNA complex; complexed with dms, edo, k8d
      3. 3076705Domain d6n0ra1: 6n0r A:162-350 [376767]
        automated match to d1qzqa1
        protein/DNA complex; complexed with dms, edo, k8d
      4. 3076706Domain d6n0ra2: 6n0r A:351-607 [376768]
        automated match to d1qzqa2
        protein/DNA complex; complexed with dms, edo, k8d
    31. Domains for 6n17:
      1. 3070589Domain d6n17b1: 6n17 B:162-350 [370651]
        automated match to d1qzqa1
        protein/DNA complex; complexed with dms, edo, k8y
      2. 3070590Domain d6n17b2: 6n17 B:351-607 [370652]
        automated match to d1qzqa2
        protein/DNA complex; complexed with dms, edo, k8y
      3. 3070601Domain d6n17a1: 6n17 A:162-350 [370663]
        automated match to d1qzqa1
        protein/DNA complex; complexed with dms, edo, k8y
      4. 3070602Domain d6n17a2: 6n17 A:351-607 [370664]
        automated match to d1qzqa2
        protein/DNA complex; complexed with dms, edo, k8y
    32. Domains for 6n19:
      1. 3070628Domain d6n19b1: 6n19 B:162-350 [370690]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k8v
      2. 3070629Domain d6n19b2: 6n19 B:351-607 [370691]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k8v
      3. 3070641Domain d6n19a1: 6n19 A:162-350 [370703]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, k8v
      4. 3070642Domain d6n19a2: 6n19 A:351-607 [370704]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, k8v
    33. Domains for 6w4r:
      1. 3102583Domain d6w4rb1: 6w4r B:162-350 [402645]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, mpo, szv
      2. 3102584Domain d6w4rb2: 6w4r B:351-607 [402646]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, mpo, szv
      3. 3102600Domain d6w4ra1: 6w4r A:162-350 [402662]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, mpo, szv
      4. 3102601Domain d6w4ra2: 6w4r A:351-607 [402663]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, mpo, szv
    34. Domains for 6w7j:
      1. 3102570Domain d6w7ja1: 6w7j A:162-350 [402632]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, tgm
      2. 3102571Domain d6w7ja2: 6w7j A:351-607 [402633]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, tgm
      3. 3102574Domain d6w7jb1: 6w7j B:162-350 [402636]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, tgm
      4. 3102575Domain d6w7jb2: 6w7j B:351-607 [402637]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, tgm
    35. Domains for 6w7k:
      1. 3102596Domain d6w7kb1: 6w7k B:162-350 [402658]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, tg7
      2. 3102597Domain d6w7kb2: 6w7k B:351-607 [402659]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, tg7
      3. 3102603Domain d6w7ka1: 6w7k A:162-350 [402665]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, tg7
      4. 3102604Domain d6w7ka2: 6w7k A:351-607 [402666]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, tg7
    36. Domains for 6w7l:
      1. 3102586Domain d6w7la1: 6w7l A:162-350 [402648]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, tgv
      2. 3102587Domain d6w7la2: 6w7l A:351-607 [402649]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, tgv
      3. 3102635Domain d6w7lb1: 6w7l B:162-350 [402697]
        automated match to d1qzqa1
        protein/DNA complex; complexed with edo, tgv
      4. 3102636Domain d6w7lb2: 6w7l B:351-607 [402698]
        automated match to d1qzqa2
        protein/DNA complex; complexed with edo, tgv

More info for Protein Tyrosyl-DNA phosphodiesterase TDP1 from d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1

Timeline for Protein Tyrosyl-DNA phosphodiesterase TDP1 from d.136.1.3: Tyrosyl-DNA phosphodiesterase TDP1: