SCOPe 2.02: Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain

Lineage for Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (4 families)

5. Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain [69804] (2 proteins)

Proteins:

1. Branched-chain alpha-ketoacid dehydrogenase kinase (BCK) [69805] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [69806] (3 PDB entries)

2. Pyruvate dehydrogenase kinase [69807] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [160702] (5 PDB entries)
      Uniprot Q15120 177-301

   2. Species Rat (Rattus norvegicus), isozyme 2 [TaxId:10116] [69808] (1 PDB entry)

More info for Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain

Timeline for Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain:

• Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain first appeared in SCOP 1.59
  
• Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain appears in SCOPe 2.01
  
• Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain appears in SCOPe 2.03
  
• Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain appears in the current release, SCOPe 2.08