SCOPe 2.03: Protein: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD)

Lineage for Protein: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD)

Root: SCOPe 2.03
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

Fold c.72: Ribokinase-like [53612] (3 superfamilies)
core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
potential superfamily: members of this fold have similar functions but different ATP-binding sites

Superfamily c.72.1: Ribokinase-like [53613] (6 families)
has extra strand located between strands 2 and 3
Family c.72.1.2: Thiamin biosynthesis kinases [53620] (2 proteins)
Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) [69589] (2 species)

Species:

Salmonella typhimurium [TaxId:90371] [69590] (2 PDB entries)
1. Domains for 1jxh:
  1. Domain d1jxha_: 1jxh A: [67415]
    complexed with so4
  2. Domain d1jxhb_: 1jxh B: [67416]
    complexed with so4
2. Domains for 1jxi:
  1. Domain d1jxia_: 1jxi A: [67417]
    complexed with hmh, so4
  2. Domain d1jxib_: 1jxi B: [67418]
    complexed with hmh, so4
Thermus thermophilus [TaxId:274] [89775] (1 PDB entry)
- Domain for 1ub0:
  - Domain d1ub0a_: 1ub0 A: [88394]
    structural genomics
    complexed with dio, gol, so4

More info for Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases

Timeline for Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases:

Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases first appeared in SCOP 1.59
Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases appears in SCOPe 2.02
Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases appears in SCOPe 2.04
Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases appears in the current release, SCOPe 2.08