Lineage for Protein: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2137471Fold c.72: Ribokinase-like [53612] (3 superfamilies)
    core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
    potential superfamily: members of this fold have similar functions but different ATP-binding sites
  4. 2137472Superfamily c.72.1: Ribokinase-like [53613] (6 families) (S)
    has extra strand located between strands 2 and 3
  5. 2137573Family c.72.1.2: Thiamin biosynthesis kinases [53620] (2 protein domains)
  6. 2137574Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) [69589] (2 species)

Species:

  1. 2137575Salmonella typhimurium [TaxId:90371] [69590] (2 PDB entries)
    1. Domains for 1jxh:
      1. 2137576Domain d1jxha_: 1jxh A: [67415]
        complexed with so4
      2. 2137577Domain d1jxhb_: 1jxh B: [67416]
        complexed with so4
    2. Domains for 1jxi:
      1. 2137578Domain d1jxia_: 1jxi A: [67417]
        complexed with hmh, so4
      2. 2137579Domain d1jxib_: 1jxi B: [67418]
        complexed with hmh, so4
  2. 2137580Thermus thermophilus [TaxId:274] [89775] (1 PDB entry)

More info for Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases

Timeline for Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases:

  • Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases first appeared in SCOP 1.59
  • Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) from c.72.1.2: Thiamin biosynthesis kinases appears in SCOPe 2.05