SCOPe 2.06: Family c.66.1.18: Mycolic acid cyclopropane synthase

Lineage for Family c.66.1.18: Mycolic acid cyclopropane synthase

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.18: Mycolic acid cyclopropane synthase [69560] (7 proteins)

Proteins:

1. CmaA1 [69561] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [69562] (3 PDB entries)

2. CmaA2 [116723] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [116724] (1 PDB entry)

3. Methoxy mycolic acid synthase 2, Mma2 [117681] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [117682] (1 PDB entry)
     Uniprot P72026 33-317

4. Methoxy mycolic acid synthase 4, Mma4 [142591] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [142592] (5 PDB entries)
     Uniprot Q79FX8 22-301

5. PccA [75269] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [75270] (1 PDB entry)

6. Putative sarcosine dimethylglycine methyltransferase [159680] (1 species)
   sequence similarity to other families with less structural similarity

   • Species Red algae (Galdieria sulphuraria) [TaxId:130081] [159681] (1 PDB entry)

7. automated matches [191052] (1 species)
   not a true protein

   • Species Mycobacterium tuberculosis [TaxId:1773] [188911] (1 PDB entry)

More info for Family c.66.1.18: Mycolic acid cyclopropane synthase

Timeline for Family c.66.1.18: Mycolic acid cyclopropane synthase:

• Family c.66.1.18: Mycolic acid cyclopropane synthase first appeared in SCOP 1.59, called Family c.66.1.18: Mycolic acid cyclopropane synthase CmaA1
  
• Family c.66.1.18: Mycolic acid cyclopropane synthase appears in SCOPe 2.05
  
• Family c.66.1.18: Mycolic acid cyclopropane synthase appears in SCOPe 2.07
  
• Family c.66.1.18: Mycolic acid cyclopropane synthase appears in the current release, SCOPe 2.08