Lineage for Species: Archaeon Pyrobaculum aerophilum [TaxId: 13773]
- Root: SCOP 1.75
Class c: Alpha and beta proteins (a/b) [51349] (147 folds) 
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) 
there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
Family c.36.1.7: Branched-chain alpha-keto acid dehydrogenase Pyr module [88741] (4 proteins)
parent family to TK and PFOR
heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
Protein E1-beta subunit of pyruvate dehydrogenase, Pyr module [69472] (2 species) 
Species Archaeon Pyrobaculum aerophilum [TaxId:13773] [69473] (1 PDB entry)
PDB entry in Species: Archaeon Pyrobaculum aerophilum [TaxId: 13773]:
- Domain(s) for 1ik6:
Domain d1ik6a1: 1ik6 A:1-191 [66174]
Other proteins in same PDB: d1ik6a2
structure determined on its own rather in the complex with E1-alpha
More info for Species Archaeon Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module
Timeline for Species Archaeon Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module:
- Species Archaeon Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module first appeared in SCOP 1.59, called Species Archaeon Pyrobaculum aerophilum [TaxId:13773] from c.36.1.3 E1-beta subunit of pyruvate dehydrogenase
- Species Archaeon Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module appears in SCOP 1.73
- Species Archaeon Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module is called Species Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module in SCOPe 2.01
- Species Archaeon Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module appears in the current release, SCOPe 2.08, called Species Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module