Lineage for Species: Pyrobaculum aerophilum [TaxId: 13773]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108430Family c.36.1.7: Branched-chain alpha-keto acid dehydrogenase Pyr module [88741] (5 protein domains)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
    automatically mapped to Pfam PF02779
  6. 2108468Protein E1-beta subunit of pyruvate dehydrogenase, Pyr module [69472] (2 species)
  7. 2108494Species Pyrobaculum aerophilum [TaxId:13773] [69473] (1 PDB entry)

PDB entry in Species: Pyrobaculum aerophilum [TaxId: 13773]:

  • Domain(s) for 1ik6:
    • 2108495Domain d1ik6a1: 1ik6 A:1-191 [66174]
      Other proteins in same PDB: d1ik6a2
      structure determined on its own rather in the complex with E1-alpha

More info for Species Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module

Timeline for Species Pyrobaculum aerophilum [TaxId:13773] from c.36.1.7 E1-beta subunit of pyruvate dehydrogenase, Pyr module: