SCOP 1.63: Protein: Acetohydroxyacid synthase catalytic subunit

Lineage for Protein: Acetohydroxyacid synthase catalytic subunit

Root: SCOP 1.63
Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465

Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (4 families)

both pyridine (Pyr)- and pyrophosphate (PP)-binding modules have this fold
conserved core consists of two Pyr and two PP-modules and binds two coenzyme molecules

Family c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains [52519] (4 proteins)
the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology

Protein Acetohydroxyacid synthase catalytic subunit [69470] (1 species)

Species:

Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69471] (2 PDB entries)
1. Domains for 1jsc:
  1. Domain d1jsca2: 1jsc A:83-270 [67225]
    Other proteins in same PDB: d1jsca1, d1jscb1
  2. Domain d1jsca3: 1jsc A:461-648 [67226]
    Other proteins in same PDB: d1jsca1, d1jscb1
  3. Domain d1jscb2: 1jsc B:82-272 [67228]
    Other proteins in same PDB: d1jsca1, d1jscb1
  4. Domain d1jscb3: 1jsc B:464-649 [67229]
    Other proteins in same PDB: d1jsca1, d1jscb1
    complexed with 2hp, fad, k, mg, tpp
2. Domains for 1n0h:
  1. Domain d1n0ha2: 1n0h A:83-270 [79735]
    Other proteins in same PDB: d1n0ha1, d1n0hb1
  2. Domain d1n0ha3: 1n0h A:461-687 [79736]
    Other proteins in same PDB: d1n0ha1, d1n0hb1
  3. Domain d1n0hb2: 1n0h B:83-270 [79738]
    Other proteins in same PDB: d1n0ha1, d1n0hb1
  4. Domain d1n0hb3: 1n0h B:461-687 [79739]
    Other proteins in same PDB: d1n0ha1, d1n0hb1
    complexed with ayd, cie, dtt, fad, k, mg, tpp

More info for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains

Timeline for Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains:

Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains first appeared in SCOP 1.59, called Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.1: Pyruvate oxidase and decarboxylase
Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains was called Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.1: Pyruvate oxidase and decarboxylase in SCOP 1.61
Protein Acetohydroxyacid synthase catalytic subunit from c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains does not appear in SCOP 1.65