SCOPe 2.05: Protein: Acetohydroxyacid synthase catalytic subunit

Lineage for Protein: Acetohydroxyacid synthase catalytic subunit

Root: SCOPe 2.05
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
binds cofactor molecules in the opposite direction than classical Rossmann fold
Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 proteins)
N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
Protein Acetohydroxyacid synthase catalytic subunit [69463] (2 species)

Species:

Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69464] (6 PDB entries)
Uniprot P07342 84-687
1. Domains for 1jsc:
  1. Domain d1jsca1: 1jsc A:280-460 [67224]
    Other proteins in same PDB: d1jsca2, d1jsca3, d1jscb2, d1jscb3
    complexed with 2hp, fad, k, mg, tpp
  2. Domain d1jscb1: 1jsc B:276-458 [67227]
    Other proteins in same PDB: d1jsca2, d1jsca3, d1jscb2, d1jscb3
    complexed with 2hp, fad, k, mg, tpp
2. Domains for 1n0h:
  1. Domain d1n0ha1: 1n0h A:277-460 [79734]
    Other proteins in same PDB: d1n0ha2, d1n0ha3, d1n0hb2, d1n0hb3
    complexed with ayd, cie, dtt, fad, k, mg, tpp
  2. Domain d1n0hb1: 1n0h B:278-460 [79737]
    Other proteins in same PDB: d1n0ha2, d1n0ha3, d1n0hb2, d1n0hb3
    complexed with ayd, cie, dtt, fad, k, mg, tpp
3. Domains for 1t9a:
  1. Domain d1t9aa1: 1t9a A:277-460 [112328]
    Other proteins in same PDB: d1t9aa2, d1t9aa3, d1t9ab2, d1t9ab3
    complexed with 1tb, fad, k, mg, p23, yf3, yf4
  2. Domain d1t9ab1: 1t9a B:281-460 [112331]
    Other proteins in same PDB: d1t9aa2, d1t9aa3, d1t9ab2, d1t9ab3
    complexed with 1tb, fad, k, mg, p23, yf3, yf4
4. Domains for 1t9b:
  1. Domain d1t9ba1: 1t9b A:284-460 [112334]
    Other proteins in same PDB: d1t9ba2, d1t9ba3, d1t9bb2, d1t9bb3
    complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
  2. Domain d1t9bb1: 1t9b B:278-460 [112337]
    Other proteins in same PDB: d1t9ba2, d1t9ba3, d1t9bb2, d1t9bb3
    complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
5. Domains for 1t9c:
  1. Domain d1t9ca1: 1t9c A:278-460 [112340]
    Other proteins in same PDB: d1t9ca2, d1t9ca3, d1t9cb2, d1t9cb3
    complexed with 1sm, fad, k, mg, p22, p23
  2. Domain d1t9cb1: 1t9c B:281-460 [112343]
    Other proteins in same PDB: d1t9ca2, d1t9ca3, d1t9cb2, d1t9cb3
    complexed with 1sm, fad, k, mg, p22, p23
6. Domains for 1t9d:
  1. Domain d1t9da1: 1t9d A:277-460 [112346]
    Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
    complexed with 1mm, fad, k, mg, p22, p25, pyd
  2. Domain d1t9db1: 1t9d B:284-460 [112349]
    Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
    complexed with 1mm, fad, k, mg, p22, p25, pyd
  3. Domain d1t9dc1: 1t9d C:290-460 [112352]
    Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
    complexed with 1mm, fad, k, mg, p22, p25, pyd
  4. Domain d1t9dd1: 1t9d D:290-460 [112355]
    Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
    complexed with 1mm, fad, k, mg, p22, p25, pyd
Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142123] (6 PDB entries)
Uniprot P17597 281-459
1. Domain for 1ybh:
  - Domain d1ybha1: 1ybh A:281-459 [122891]
    Other proteins in same PDB: d1ybha2, d1ybha3
    complexed with cie, fad, mg, nhe, p22
2. Domain for 1yhy:
  - Domain d1yhya1: 1yhy A:281-459 [123215]
    Other proteins in same PDB: d1yhya2, d1yhya3
    automated match to d1ybha1
    complexed with 1mm, fad, mg, nhe, p22
3. Domain for 1yhz:
  - Domain d1yhza1: 1yhz A:281-459 [123218]
    Other proteins in same PDB: d1yhza2, d1yhza3
    automated match to d1ybha1
    complexed with 1cs, fad, mg, nhe, p22
4. Domain for 1yi0:
  - Domain d1yi0a1: 1yi0 A:281-459 [123221]
    Other proteins in same PDB: d1yi0a2, d1yi0a3
    automated match to d1ybha1
    complexed with 1sm, fad, mg, nhe, p22
5. Domain for 1yi1:
  - Domain d1yi1a1: 1yi1 A:281-459 [123224]
    Other proteins in same PDB: d1yi1a2, d1yi1a3
    automated match to d1ybha1
    complexed with 1tb, fad, mg, nhe, p22
6. Domain for 1z8n:
  - Domain d1z8na1: 1z8n A:281-459 [124719]
    Other proteins in same PDB: d1z8na2, d1z8na3
    automated match to d1ybha1
    complexed with 1iq, fad, mg, nhe, tpp

More info for Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain:

Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain first appeared in SCOP 1.59
Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOPe 2.04
Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOPe 2.06
Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in the current release, SCOPe 2.08