Lineage for Protein: Acetohydroxyacid synthase catalytic subunit

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 694236Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 694237Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (6 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 694262Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 proteins)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
  6. 694263Protein Acetohydroxyacid synthase catalytic subunit [69463] (2 species)

Species:

  1. 694264Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69464] (6 PDB entries)
    1. Domains for 1jsc:
      1. 694275Domain d1jsca1: 1jsc A:280-460 [67224]
        Other proteins in same PDB: d1jsca2, d1jsca3, d1jscb2, d1jscb3
      2. 694276Domain d1jscb1: 1jsc B:276-458 [67227]
        Other proteins in same PDB: d1jsca2, d1jsca3, d1jscb2, d1jscb3
        complexed with 2hp, fad, k, mg, tpp
    2. Domains for 1n0h:
      1. 694277Domain d1n0ha1: 1n0h A:277-460 [79734]
        Other proteins in same PDB: d1n0ha2, d1n0ha3, d1n0hb2, d1n0hb3
      2. 694278Domain d1n0hb1: 1n0h B:278-460 [79737]
        Other proteins in same PDB: d1n0ha2, d1n0ha3, d1n0hb2, d1n0hb3
        complexed with ayd, cie, dtt, fad, k, mg, tpp
    3. Domains for 1t9a:
      1. 694273Domain d1t9aa1: 1t9a A:290-460 [112328]
        Other proteins in same PDB: d1t9aa2, d1t9aa3, d1t9ab2, d1t9ab3
      2. 694274Domain d1t9ab1: 1t9a B:290-460 [112331]
        Other proteins in same PDB: d1t9aa2, d1t9aa3, d1t9ab2, d1t9ab3
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
    4. Domains for 1t9b:
      1. 694265Domain d1t9ba1: 1t9b A:290-460 [112334]
        Other proteins in same PDB: d1t9ba2, d1t9ba3, d1t9bb2, d1t9bb3
      2. 694266Domain d1t9bb1: 1t9b B:290-460 [112337]
        Other proteins in same PDB: d1t9ba2, d1t9ba3, d1t9bb2, d1t9bb3
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
    5. Domains for 1t9c:
      1. 694271Domain d1t9ca1: 1t9c A:290-460 [112340]
        Other proteins in same PDB: d1t9ca2, d1t9ca3, d1t9cb2, d1t9cb3
      2. 694272Domain d1t9cb1: 1t9c B:290-460 [112343]
        Other proteins in same PDB: d1t9ca2, d1t9ca3, d1t9cb2, d1t9cb3
        complexed with 1sm, fad, k, mg, p22, p23
    6. Domains for 1t9d:
      1. 694267Domain d1t9da1: 1t9d A:290-460 [112346]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
      2. 694268Domain d1t9db1: 1t9d B:290-460 [112349]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
      3. 694269Domain d1t9dc1: 1t9d C:290-460 [112352]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
      4. 694270Domain d1t9dd1: 1t9d D:290-460 [112355]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, yf1
  2. 694279Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142123] (6 PDB entries)
    1. Domain for 1ybh:
    2. Domain for 1yhy:
    3. Domain for 1yhz:
    4. Domain for 1yi0:
    5. Domain for 1yi1:
    6. Domain for 1z8n:

More info for Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain:

  • Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain first appeared in SCOP 1.59
  • Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOP 1.71
  • Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOP 1.75
  • Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in the current release, SCOPe 2.07