Lineage for Protein: Acetohydroxyacid synthase catalytic subunit

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2107255Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2107256Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2107283Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 protein domains)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
  6. 2107284Protein Acetohydroxyacid synthase catalytic subunit [69463] (3 species)

Species:

  1. 2107285Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69464] (10 PDB entries)
    Uniprot P07342 84-687
    1. Domains for 1jsc:
      1. 2107296Domain d1jsca1: 1jsc A:280-460 [67224]
        Other proteins in same PDB: d1jsca2, d1jsca3, d1jscb2, d1jscb3
        complexed with 2hp, fad, k, mg, tpp
      2. 2107297Domain d1jscb1: 1jsc B:276-458 [67227]
        Other proteins in same PDB: d1jsca2, d1jsca3, d1jscb2, d1jscb3
        complexed with 2hp, fad, k, mg, tpp
    2. Domains for 1n0h:
      1. 2107298Domain d1n0ha1: 1n0h A:277-460 [79734]
        Other proteins in same PDB: d1n0ha2, d1n0ha3, d1n0hb2, d1n0hb3
        complexed with ayd, cie, dtt, fad, k, mg, tpp
      2. 2107299Domain d1n0hb1: 1n0h B:278-460 [79737]
        Other proteins in same PDB: d1n0ha2, d1n0ha3, d1n0hb2, d1n0hb3
        complexed with ayd, cie, dtt, fad, k, mg, tpp
    3. Domains for 1t9a:
      1. 2107294Domain d1t9aa1: 1t9a A:277-460 [112328]
        Other proteins in same PDB: d1t9aa2, d1t9aa3, d1t9ab2, d1t9ab3
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
      2. 2107295Domain d1t9ab1: 1t9a B:281-460 [112331]
        Other proteins in same PDB: d1t9aa2, d1t9aa3, d1t9ab2, d1t9ab3
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
    4. Domains for 1t9b:
      1. 2107286Domain d1t9ba1: 1t9b A:284-460 [112334]
        Other proteins in same PDB: d1t9ba2, d1t9ba3, d1t9bb2, d1t9bb3
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
      2. 2107287Domain d1t9bb1: 1t9b B:278-460 [112337]
        Other proteins in same PDB: d1t9ba2, d1t9ba3, d1t9bb2, d1t9bb3
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
    5. Domains for 1t9c:
      1. 2107292Domain d1t9ca1: 1t9c A:278-460 [112340]
        Other proteins in same PDB: d1t9ca2, d1t9ca3, d1t9cb2, d1t9cb3
        complexed with 1sm, fad, k, mg, p22, p23
      2. 2107293Domain d1t9cb1: 1t9c B:281-460 [112343]
        Other proteins in same PDB: d1t9ca2, d1t9ca3, d1t9cb2, d1t9cb3
        complexed with 1sm, fad, k, mg, p22, p23
    6. Domains for 1t9d:
      1. 2107288Domain d1t9da1: 1t9d A:277-460 [112346]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      2. 2107289Domain d1t9db1: 1t9d B:284-460 [112349]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      3. 2107290Domain d1t9dc1: 1t9d C:290-460 [112352]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      4. 2107291Domain d1t9dd1: 1t9d D:290-460 [112355]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
    7. Domains for 5inu:
      1. 2286526Domain d5inub2: 5inu B:277-460 [329827]
        Other proteins in same PDB: d5inua1, d5inub1
        automated match to d1n0ha1
        complexed with fad, k, mg, oxy, po4, pyr, tpp
      2. 2286593Domain d5inua2: 5inu A:277-460 [329894]
        Other proteins in same PDB: d5inua1, d5inub1
        automated match to d1n0ha1
        complexed with fad, k, mg, oxy, po4, pyr, tpp
    8. Domains for 5inv:
      1. 2286457Domain d5inva2: 5inv A:282-460 [329758]
        Other proteins in same PDB: d5inva1, d5invb1
        automated match to d1n0ha1
        complexed with bct, co2, fad, htl, k, mg, oxy, po4, tpp
      2. 2286484Domain d5invb2: 5inv B:275-460 [329785]
        Other proteins in same PDB: d5inva1, d5invb1
        automated match to d1n0ha1
        complexed with bct, co2, fad, htl, k, mg, oxy, po4, tpp
    9. Domains for 6bd3:
      1. 2297896Domain d6bd3b2: 6bd3 B:275-460 [341197]
        Other proteins in same PDB: d6bd3a1, d6bd3b1
        automated match to d1n0ha1
        complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp
      2. 2297897Domain d6bd3a2: 6bd3 A:282-460 [341198]
        Other proteins in same PDB: d6bd3a1, d6bd3b1
        automated match to d1n0ha1
        complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp
    10. Domains for 6bd9:
      1. 2297994Domain d6bd9a2: 6bd9 A:280-460 [341295]
        Other proteins in same PDB: d6bd9a1, d6bd9b1
        automated match to d1n0ha1
        complexed with fad, k, mg, oxy, po4, pyr, tpp
      2. 2298050Domain d6bd9b2: 6bd9 B:277-460 [341351]
        Other proteins in same PDB: d6bd9a1, d6bd9b1
        automated match to d1n0ha1
        complexed with fad, k, mg, oxy, po4, pyr, tpp
  2. 2107300Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142123] (11 PDB entries)
    Uniprot P17597 281-459
    1. Domain for 1ybh:
    2. Domain for 1yhy:
    3. Domain for 1yhz:
    4. Domain for 1yi0:
    5. Domain for 1yi1:
    6. Domain for 1z8n:
    7. Domain for 5k2o:
    8. Domain for 5k3s:
    9. Domain for 5k6q:
    10. Domain for 5k6r:
    11. Domain for 5k6t:
  3. 2270803Saccharomyces cerevisiae [TaxId:559292] [314108] (2 PDB entries)
    1. Domains for 5fem:
      1. 2270804Domain d5femb2: 5fem B:277-460 [314109]
        Other proteins in same PDB: d5fema1, d5fema3, d5femb1, d5femb3
        automated match to d1n0ha1
        complexed with 60g, fad, mg, tpp
      2. 2270817Domain d5fema2: 5fem A:277-460 [314122]
        Other proteins in same PDB: d5fema1, d5fema3, d5femb1, d5femb3
        automated match to d1n0ha1
        complexed with 60g, fad, mg, tpp
    2. Domains for 5ims:
      1. 2286426Domain d5imsa2: 5ims A:279-460 [329727]
        Other proteins in same PDB: d5imsa1, d5imsb1
        automated match to d1n0ha1
        complexed with act, fad, k, mg, oxy, po4, tpp
      2. 2286499Domain d5imsb2: 5ims B:277-460 [329800]
        Other proteins in same PDB: d5imsa1, d5imsb1
        automated match to d1n0ha1
        complexed with act, fad, k, mg, oxy, po4, tpp

More info for Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain:

  • Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain first appeared in SCOP 1.59
  • Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOPe 2.05