Lineage for Protein: Acetohydroxyacid synthase catalytic subunit

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2444630Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2444631Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2444658Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 protein domains)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
  6. 2444659Protein Acetohydroxyacid synthase catalytic subunit [69463] (3 species)

Species:

  1. 2444660Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69464] (8 PDB entries)
    Uniprot P07342 84-687
    1. Domains for 1jsc:
      1. 2444661Domain d1jsca1: 1jsc A:280-460 [67224]
        Other proteins in same PDB: d1jsca2, d1jsca3, d1jscb2, d1jscb3
        complexed with 2hp, fad, k, mg, tpp
      2. 2444662Domain d1jscb1: 1jsc B:276-458 [67227]
        Other proteins in same PDB: d1jsca2, d1jsca3, d1jscb2, d1jscb3
        complexed with 2hp, fad, k, mg, tpp
    2. Domains for 1n0h:
      1. 2444677Domain d1n0ha1: 1n0h A:277-460 [79734]
        Other proteins in same PDB: d1n0ha2, d1n0ha3, d1n0hb2, d1n0hb3
        complexed with ayd, cie, dtt, fad, k, mg, tpp
      2. 2444678Domain d1n0hb1: 1n0h B:278-460 [79737]
        Other proteins in same PDB: d1n0ha2, d1n0ha3, d1n0hb2, d1n0hb3
        complexed with ayd, cie, dtt, fad, k, mg, tpp
    3. Domains for 1t9a:
      1. 2444675Domain d1t9aa1: 1t9a A:277-460 [112328]
        Other proteins in same PDB: d1t9aa2, d1t9aa3, d1t9ab2, d1t9ab3
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
      2. 2444676Domain d1t9ab1: 1t9a B:281-460 [112331]
        Other proteins in same PDB: d1t9aa2, d1t9aa3, d1t9ab2, d1t9ab3
        complexed with 1tb, fad, k, mg, p23, yf3, yf4
    4. Domains for 1t9b:
      1. 2444665Domain d1t9ba1: 1t9b A:284-460 [112334]
        Other proteins in same PDB: d1t9ba2, d1t9ba3, d1t9bb2, d1t9bb3
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
      2. 2444666Domain d1t9bb1: 1t9b B:278-460 [112337]
        Other proteins in same PDB: d1t9ba2, d1t9ba3, d1t9bb2, d1t9bb3
        complexed with 1cs, fad, k, mg, nsp, p22, p25, yf3
    5. Domains for 1t9c:
      1. 2444673Domain d1t9ca1: 1t9c A:278-460 [112340]
        Other proteins in same PDB: d1t9ca2, d1t9ca3, d1t9cb2, d1t9cb3
        complexed with 1sm, fad, k, mg, p22, p23
      2. 2444674Domain d1t9cb1: 1t9c B:281-460 [112343]
        Other proteins in same PDB: d1t9ca2, d1t9ca3, d1t9cb2, d1t9cb3
        complexed with 1sm, fad, k, mg, p22, p23
    6. Domains for 1t9d:
      1. 2444669Domain d1t9da1: 1t9d A:277-460 [112346]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      2. 2444670Domain d1t9db1: 1t9d B:284-460 [112349]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      3. 2444671Domain d1t9dc1: 1t9d C:290-460 [112352]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
      4. 2444672Domain d1t9dd1: 1t9d D:290-460 [112355]
        Other proteins in same PDB: d1t9da2, d1t9da3, d1t9db2, d1t9db3, d1t9dc2, d1t9dc3, d1t9dd2, d1t9dd3
        complexed with 1mm, fad, k, mg, p22, p25, pyd
    7. Domains for 6bd3:
      1. 2444667Domain d6bd3a2: 6bd3 A:282-460 [341198]
        Other proteins in same PDB: d6bd3a1, d6bd3a3, d6bd3b1, d6bd3b3
        automated match to d1n0ha1
        complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp
      2. 2444668Domain d6bd3b2: 6bd3 B:275-460 [341197]
        Other proteins in same PDB: d6bd3a1, d6bd3a3, d6bd3b1, d6bd3b3
        automated match to d1n0ha1
        complexed with act, co2, fad, htl, k, mg, oxy, po4, tpp
    8. Domains for 6bd9:
      1. 2444663Domain d6bd9a2: 6bd9 A:280-460 [341295]
        Other proteins in same PDB: d6bd9a1, d6bd9a3, d6bd9b1, d6bd9b3
        automated match to d1n0ha1
        complexed with fad, k, mg, oxy, po4, pyr, tpp
      2. 2444664Domain d6bd9b2: 6bd9 B:277-460 [341351]
        Other proteins in same PDB: d6bd9a1, d6bd9a3, d6bd9b1, d6bd9b3
        automated match to d1n0ha1
        complexed with fad, k, mg, oxy, po4, pyr, tpp
  2. 2444679Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [314108] (3 PDB entries)
    1. Domains for 5fem:
      1. 2444682Domain d5fema2: 5fem A:277-460 [314122]
        Other proteins in same PDB: d5fema1, d5fema3, d5femb1, d5femb3
        automated match to d1n0ha1
        complexed with 60g, fad, mg, tpp
      2. 2444683Domain d5femb2: 5fem B:277-460 [314109]
        Other proteins in same PDB: d5fema1, d5fema3, d5femb1, d5femb3
        automated match to d1n0ha1
        complexed with 60g, fad, mg, tpp
    2. Domains for 5ims:
      1. 2444680Domain d5imsa2: 5ims A:279-460 [329727]
        Other proteins in same PDB: d5imsa1, d5imsa3, d5imsb1, d5imsb3
        automated match to d1n0ha1
        complexed with act, fad, k, mg, oxy, po4, tpp
      2. 2444681Domain d5imsb2: 5ims B:277-460 [329800]
        Other proteins in same PDB: d5imsa1, d5imsa3, d5imsb1, d5imsb3
        automated match to d1n0ha1
        complexed with act, fad, k, mg, oxy, po4, tpp
    3. Domains for 5wkc:
      1. 3048135Domain d5wkca2: 5wkc A:280-460 [348197]
        Other proteins in same PDB: d5wkca1, d5wkca3, d5wkcb1, d5wkcb3, d5wkcd1, d5wkcd3, d5wkce1, d5wkce3
        automated match to d1n0ha1
        complexed with auj, f50, fad, mg, pxd, tp9
      2. 3048155Domain d5wkcd2: 5wkc D:278-460 [348217]
        Other proteins in same PDB: d5wkca1, d5wkca3, d5wkcb1, d5wkcb3, d5wkcd1, d5wkcd3, d5wkce1, d5wkce3
        automated match to d1n0ha1
        complexed with auj, f50, fad, mg, pxd, tp9
      3. 3048241Domain d5wkce2: 5wkc E:282-460 [348303]
        Other proteins in same PDB: d5wkca1, d5wkca3, d5wkcb1, d5wkcb3, d5wkcd1, d5wkcd3, d5wkce1, d5wkce3
        automated match to d1n0ha1
        complexed with auj, f50, fad, mg, pxd, tp9
      4. 3048285Domain d5wkcb2: 5wkc B:277-460 [348347]
        Other proteins in same PDB: d5wkca1, d5wkca3, d5wkcb1, d5wkcb3, d5wkcd1, d5wkcd3, d5wkce1, d5wkce3
        automated match to d1n0ha1
        complexed with auj, f50, fad, mg, pxd, tp9
  3. 2444684Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142123] (12 PDB entries)
    Uniprot P17597 281-459
    1. Domain for 1ybh:
    2. Domain for 1yhy:
    3. Domain for 1yhz:
    4. Domain for 1yi0:
    5. Domain for 1yi1:
    6. Domain for 1z8n:
    7. Domain for 5k2o:
    8. Domain for 5k3s:
    9. Domain for 5k6q:
    10. Domain for 5k6r:
    11. Domain for 5k6t:
    12. Domain for 5wj1:

More info for Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain:

  • Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain first appeared in SCOP 1.59
  • Protein Acetohydroxyacid synthase catalytic subunit from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOPe 2.06