SCOPe 2.05: Superfamily a.152.1: AhpD-like

Lineage for Superfamily a.152.1: AhpD-like

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.152: AhpD-like [69117] (1 superfamily)
   multihelical; contains 4-helical bundle and 2-helical arm

4. Superfamily a.152.1: AhpD-like [69118] (4 families)
   probable biological unit contains six domains of this fold arranged with 32 symmetry

Families:

1. a.152.1.1: AhpD [69119] (2 proteins)
   duplication: two-domain subunits form a helix-swapped trimer

2. a.152.1.2: CMD-like [101468] (2 proteins)
   Pfam PF02627; hexamer of single-domain subunits

3. a.152.1.3: Atu0492-like [140970] (6 proteins)
   duplication: similar subunit structure to the AhpD family, but the putative active site is conserved in different relative location; new hexameric architecture; similar dimeric interface to the CMD-like family

4. a.152.1.4: TTHA0727-like [140975] (2 proteins)
   similar to the CMD-like family by the subunit sequence and hexameric architecture; the segment-swapped subunit fold is similar to the AhpD domains

More info for Superfamily a.152.1: AhpD-like

Timeline for Superfamily a.152.1: AhpD-like:

• Superfamily a.152.1: AhpD-like first appeared in SCOP 1.59, called Superfamily a.152.1: Antioxidant defence protein AhpD
  
• Superfamily a.152.1: AhpD-like appears in SCOPe 2.04
  
• Superfamily a.152.1: AhpD-like appears in SCOPe 2.06
  
• Superfamily a.152.1: AhpD-like appears in the current release, SCOPe 2.08