SCOPe 2.01: Family c.68.1.13: Cytidylytransferase

Lineage for Family c.68.1.13: Cytidylytransferase

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

4. Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (20 families)

5. Family c.68.1.13: Cytidylytransferase [68901] (7 proteins)

Proteins:

1. 4-diphosphocytidyl-2C-methyl-D-erythritol (CDP-me) synthase (IspD, YgbP) [64140] (4 species)

   1. Species Escherichia coli [TaxId:562] [64141] (6 PDB entries)

   2. Species Neisseria gonorrhoeae [TaxId:485] [102605] (2 PDB entries)

   3. Species Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142690] (1 PDB entry)
      Uniprot P69834 75-300

   4. Species Thermotoga maritima [TaxId:2336] [117699] (1 PDB entry)
      Uniprot Q9X1B3

2. CMP acylneuraminate synthetase [53456] (2 species)
   a sialic acid activating synthetase

   1. Species Mouse (Mus musculus) [TaxId:10090] [102608] (1 PDB entry)

   2. Species Neisseria meningitidis [TaxId:487] [53457] (2 PDB entries)

3. CMP:2-keto-3-deoxy-manno-octonic acid (CMP-KDO)synthetase [64143] (3 species)

   1. Species Escherichia coli, KdsB [TaxId:562] [102606] (1 PDB entry)

   2. Species Escherichia coli, KpsU [TaxId:562] [64144] (8 PDB entries)
      capsule-specific enzyme

   3. Species Haemophilus influenzae [TaxId:727] [102607] (2 PDB entries)

4. CTP:phosphocholine cytidylytransferase LicC [69569] (1 species)

   • Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [69570] (2 PDB entries)

5. Glucose-1-phosphate cytidylyltransferase RfbF [110689] (1 species)

   • Species Salmonella typhimurium [TaxId:90371] [110690] (2 PDB entries)
     Uniprot P26396 2-257

6. IspD/IspF bifunctional enzyme, CDP-me synthase domain [117700] (1 species)

   • Species Campylobacter jejuni [TaxId:197] [117701] (2 PDB entries)
     Uniprot Q9PM68

7. automated matches [190992] (5 species)
   not a true protein

   1. Species Escherichia coli K-12 [TaxId:83333] [189105] (2 PDB entries)

   2. Species Escherichia coli [TaxId:562] [189106] (1 PDB entry)

   3. Species Haemophilus influenzae [TaxId:727] [188698] (1 PDB entry)

   4. Species Vibrio cholerae [TaxId:243277] [189477] (1 PDB entry)

   5. Species Yersinia pestis [TaxId:214092] [189052] (1 PDB entry)

More info for Family c.68.1.13: Cytidylytransferase

Timeline for Family c.68.1.13: Cytidylytransferase:

• Family c.68.1.13: Cytidylytransferase first appeared in SCOP 1.59
  
• Family c.68.1.13: Cytidylytransferase appears in SCOP 1.75
  
• Family c.68.1.13: Cytidylytransferase appears in SCOPe 2.02
  
• Family c.68.1.13: Cytidylytransferase appears in the current release, SCOPe 2.08