SCOP 1.73: Domain d1k90c_: 1k90 C:

Lineage for d1k90c_ (1k90 C:)

1. Root: SCOP 1.73

2. Class e: Multi-domain proteins (alpha and beta) [56572] (53 folds)

3. Fold e.41: Adenylylcyclase toxin (the edema factor) [81299] (1 superfamily)
   3 domains: (1&2) alpha+beta, with domain 2 being inserted in domain 1; (3) all-alpha

4. Superfamily e.41.1: Adenylylcyclase toxin (the edema factor) [81298] (1 family)
   Domain 1 has topological and active site similarity to the Nucleotidyltransferases (eg. 1kny N-domain); domain 3 binds calmodulin

5. Family e.41.1.1: Adenylylcyclase toxin (the edema factor) [69887] (1 protein)
   decorated with many insertions and the C-terminal domain

6. Protein Adenylylcyclase toxin (the edema factor) [69888] (1 species)

7. Species Bacillus anthracis [TaxId:1392] [69889] (7 PDB entries)

8. Domain d1k90c_: 1k90 C: [68321]
   Other proteins in same PDB: d1k90d_, d1k90e_, d1k90f_
   complexed with 3at, ca, yb

Details for d1k90c_

PDB Entry: 1k90, 2.75 Å

PDB Description: crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin and 3' deoxy-atp

PDB Compounds: (C:) calmodulin-sensitive adenylate cyclase

SCOP Domain Sequences for d1k90c_:

Sequence, based on SEQRES records:

>d1k90c_ e.41.1.1 (C:) Adenylylcyclase toxin (the edema factor) {Bacillus anthracis [TaxId: 1392]}
ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksni
efkllykqlnftenetdnfevfqkiid

Sequence, based on observed residues (ATOM records):

>d1k90c_ e.41.1.1 (C:) Adenylylcyclase toxin (the edema factor) {Bacillus anthracis [TaxId: 1392]}
ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqkfkl
lykqlnftenetdnfevfqkiid

Timeline for d1k90c_:

• d1k90c_ first appeared in SCOP 1.59
  
• d1k90c_ appears in SCOP 1.71
  
• d1k90c_ appears in SCOP 1.75
  
• d1k90c_ appears in the current release, SCOPe 2.08