SCOPe 2.05: Domain d1k7le_: 1k7l E:

Lineage for d1k7le_ (1k7l E:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69110] (15 PDB entries)

8. Domain d1k7le_: 1k7l E: [68270]
   complexed with a co-activator peptide
   complexed with 544, yt3

Details for d1k7le_

PDB Entry: 1k7l, 2.5 Å

PDB Description: The 2.5 Angstrom resolution crystal structure of the human PPARalpha ligand binding domain bound with GW409544 and a co-activator peptide.

PDB Compounds: (E:) peroxisome proliferator activated receptor alpha

SCOPe Domain Sequences for d1k7le_:

Sequence; same for both SEQRES and ATOM records:

>d1k7le_ a.123.1.1 (E:) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
dlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlvaklvan
giqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaifaml
ssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislfvaa
iiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvteha
qlvqiikktesdaalhpllqeiyrdmy

Timeline for d1k7le_:

• d1k7le_ first appeared in SCOP 1.59
  
• d1k7le_ appears in SCOPe 2.04
  
• d1k7le_ appears in SCOPe 2.06
  
• d1k7le_ appears in the current release, SCOPe 2.08