SCOPe 2.04: Domain d1k70a2: 1k70 A:56-375

Lineage for d1k70a2 (1k70 A:56-375)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (19 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.5: Cytosine deaminase catalytic domain [69390] (1 protein)
   automatically mapped to Pfam PF13147
   automatically mapped to Pfam PF07969

6. Protein Cytosine deaminase catalytic domain [69391] (1 species)

7. Species Escherichia coli [TaxId:562] [69392] (8 PDB entries)
   Uniprot P25524

8. Domain d1k70a2: 1k70 A:56-375 [68250]
   Other proteins in same PDB: d1k70a1
   complexed with fe, hpy

Details for d1k70a2

PDB Entry: 1k70, 1.8 Å

PDB Description: The Structure of Escherichia coli Cytosine Deaminase bound to 4-Hydroxy-3,4-Dihydro-1H-Pyrimidin-2-one

PDB Compounds: (A:) Cytosine deaminase

SCOPe Domain Sequences for d1k70a2:

Sequence; same for both SEQRES and ATOM records:

>d1k70a2 c.1.9.5 (A:56-375) Cytosine deaminase catalytic domain {Escherichia coli [TaxId: 562]}
pfvephihldttqtagqpnwnqsgtlfegierwaerkallthddvkqrawqtlkwqiang
iqhvrthvdvsdatltalkamlevkqevapwidlqivafpqegilsypngealleealrl
gadvvgaiphfeftreygveslhktfalaqkydrlidvhcdeiddeqsrfvetvaalahh
egmgarvtashttamhsyngaytsrlfrllkmsginfvanplvnihlqgrfdtypkrrgi
trvkemlesginvcfghddvfdpwyplgtanmlqvlhmglhvcqlmgygqindglnlith
hsartlnlqdygiaagnsan

Timeline for d1k70a2:

• d1k70a2 first appeared in SCOP 1.59
  
• d1k70a2 appears in SCOPe 2.03
  
• d1k70a2 appears in SCOPe 2.05
  
• d1k70a2 appears in the current release, SCOPe 2.08