SCOP 1.75: Domain d1k6yb2: 1k6y B:56-212

Lineage for d1k6yb2 (1k6y B:56-212)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (14 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (1 protein)

6. Protein Retroviral integrase, catalytic domain [53108] (3 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53110] (18 PDB entries)

8. Domain d1k6yb2: 1k6y B:56-212 [68242]
   Other proteins in same PDB: d1k6ya1, d1k6yb1, d1k6yc1, d1k6yd1

Details for d1k6yb2

PDB Entry: 1k6y, 2.4 Å

PDB Description: Crystal Structure of a Two-Domain Fragment of HIV-1 Integrase

PDB Compounds: (B:) Pol polyprotein

SCOP Domain Sequences for d1k6yb2:

Sequence, based on SEQRES records:

>d1k6yb2 c.55.3.2 (B:56-212) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacdwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlkta
vqmavfihnkkrkggiggysagerivdiiatdiqtke

Sequence, based on observed residues (ATOM records):

>d1k6yb2 c.55.3.2 (B:56-212) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacdwagikqedgviesmnkelkkiigqvrdqaehlktavqmavfihn
kkrkggiggysagerivdiiatdiqtke

Timeline for d1k6yb2:

• d1k6yb2 first appeared in SCOP 1.59
  
• d1k6yb2 appears in SCOP 1.73
  
• d1k6yb2 appears in SCOPe 2.01
  
• d1k6yb2 appears in the current release, SCOPe 2.08