SCOPe 2.04: Domain d1jxha_: 1jxh A:

Lineage for d1jxha_ (1jxh A:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.72: Ribokinase-like [53612] (3 superfamilies)
   core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
   potential superfamily: members of this fold have similar functions but different ATP-binding sites

4. Superfamily c.72.1: Ribokinase-like [53613] (6 families)
   has extra strand located between strands 2 and 3

5. Family c.72.1.2: Thiamin biosynthesis kinases [53620] (2 proteins)

6. Protein 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) [69589] (2 species)

7. Species Salmonella typhimurium [TaxId:90371] [69590] (2 PDB entries)

8. Domain d1jxha_: 1jxh A: [67415]
   complexed with so4

Details for d1jxha_

PDB Entry: 1jxh, 2.3 Å

PDB Description: 4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase from Salmonella typhimurium

PDB Compounds: (A:) phosphomethylpyrimidine kinase

SCOPe Domain Sequences for d1jxha_:

Sequence, based on SEQRES records:

>d1jxha_ c.72.1.2 (A:) 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) {Salmonella typhimurium [TaxId: 90371]}
mqrinaltiagtdpsggagiqadlktfsalgaygcsvitalvaentcgvqsvyriepdfv
aaqldsvfsdvridttkigmlaetdiveavaerlqrhhvrnvvldtvmlaksgdpllsps
aietlrvrllpqvslitpnlpeaaalldapharteqemlaqgrallamgceavlmkgghl
edaqspdwlftregeqrfsaprvntknthgtgctlsaalaalrprhrswgetvneakawl
saalaqadtlevgkgigpvhhfhaww

Sequence, based on observed residues (ATOM records):

>d1jxha_ c.72.1.2 (A:) 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD) {Salmonella typhimurium [TaxId: 90371]}
mqrinaltiagtdpsggagiqadlktfsalgaygcsvitalvaentcgvqsvyriepdfv
aaqldsvfsdvridttkigmlaetdiveavaerlqrhhvrnvvldtvmlllspsaietlr
vrllpqvslitpnlpeaaalldapharteqemlaqgrallamgceavlmkgdwlftrege
qrfrvntknthgtgctlsaalaalrprhrswgetvneakawlsaalaqadtlevgkgigp
vhhfhaww

Timeline for d1jxha_:

• d1jxha_ first appeared in SCOP 1.59
  
• d1jxha_ appears in SCOPe 2.03
  
• d1jxha_ appears in SCOPe 2.05
  
• d1jxha_ appears in the current release, SCOPe 2.08