Lineage for d1jnnh1 (1jnn H:1-114)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2017783Species Mouse (Mus musculus), cluster 3.1 [TaxId:10090] [88551] (31 PDB entries)
    SQ NA # natural chimera; best hits are: Uniprot P01751 (Ig heavy chain V region B1-8/186-2) and Uniprot P01864 (Ig gamma-2A chain C region secreted form)
  8. 2017820Domain d1jnnh1: 1jnn H:1-114 [66960]
    Other proteins in same PDB: d1jnnh2, d1jnnl1, d1jnnl2
    part of anti-estradiol Fab 17E12E5
    complexed with est

Details for d1jnnh1

PDB Entry: 1jnn (more details), 3.2 Å

PDB Description: Crystal Structure of Fab-Estradiol Complexes
PDB Compounds: (H:) monoclonal anti-estradiol 17e12e5 immunoglobulin gamma-1 chain

SCOPe Domain Sequences for d1jnnh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1jnnh1 b.1.1.1 (H:1-114) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.1 [TaxId: 10090]}

SCOPe Domain Coordinates for d1jnnh1:

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Timeline for d1jnnh1:

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