Lineage for d1ihib_ (1ihi B:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2434695Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2437818Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2437819Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
    Common fold covers whole protein structure
  6. 2437839Protein 3-alpha-hydroxysteroid dehydrogenase [51439] (2 species)
  7. 2437840Species Human (Homo sapiens), type III [TaxId:9606] [69383] (16 PDB entries)
    bile acid binding protein
  8. 2437872Domain d1ihib_: 1ihi B: [66143]
    complexed with iu5, nap

Details for d1ihib_

PDB Entry: 1ihi (more details), 3 Å

PDB Description: Crystal Structure of Human Type III 3-alpha-Hydroxysteroid Dehydrogenase/Bile Acid Binding Protein (AKR1C2) Complexed with NADP+ and Ursodeoxycholate
PDB Compounds: (B:) 3-alpha-hydroxysteroid dehydrogenase

SCOPe Domain Sequences for d1ihib_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ihib_ c.1.7.1 (B:) 3-alpha-hydroxysteroid dehydrogenase {Human (Homo sapiens), type III [TaxId: 9606]}

SCOPe Domain Coordinates for d1ihib_:

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(The format of our PDB-style files is described here.)

Timeline for d1ihib_: