SCOPe 2.08: Domain d1igxa2: 1igx A:32-73

Lineage for d1igxa2 (1igx A:32-73)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein Prostaglandin H2 synthase-1, EGF-like module [57210] (2 species)
   the rest of protein is heme-linked peroxidase, all-alpha fold

7. Species Sheep (Ovis aries) [TaxId:9940] [57211] (23 PDB entries)
   Uniprot P05979 32-584

8. Domain d1igxa2: 1igx A:32-73 [66137]
   Other proteins in same PDB: d1igxa1
   complexed with bgc, bog, coh, epa

Details for d1igxa2

PDB Entry: 1igx, 3.1 Å

PDB Description: crystal structure of eicosapentanoic acid bound in the cyclooxygenase channel of prostaglandin endoperoxide h synthase-1.

PDB Compounds: (A:) prostaglandin endoperoxide h synthase-1

SCOPe Domain Sequences for d1igxa2:

Sequence; same for both SEQRES and ATOM records:

>d1igxa2 g.3.11.1 (A:32-73) Prostaglandin H2 synthase-1, EGF-like module {Sheep (Ovis aries) [TaxId: 9940]}
pvnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipe

Timeline for d1igxa2:

• d1igxa2 first appeared in SCOP 1.59
  
• d1igxa2 appears in SCOPe 2.07