SCOP 1.73: Domain d1i8mh1: 1i8m H:1-113

Lineage for d1i8mh1 (1i8m H:1-113)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (148 PDB entries)

8. Domain d1i8mh1: 1i8m H:1-113 [66086]
   Other proteins in same PDB: d1i8ma1, d1i8ma2, d1i8mb2, d1i8mh2, d1i8ml1, d1i8ml2

Details for d1i8mh1

PDB Entry: 1i8m, 2.1 Å

PDB Description: crystal structure of a recombinant anti-single-stranded dna antibody fragment complexed with dt5

PDB Compounds: (H:) antibody heavy chain fab

SCOP Domain Sequences for d1i8mh1:

Sequence; same for both SEQRES and ATOM records:

>d1i8mh1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
qvkllesgpelvkpgasvkmsckasgytftsyvmhwvkqkpgqglewigyinpyndgtky
nekfkgkatltsdkssstaymelssltsedsavyycvrggyrpyyamdywgqgtsvtvss

Timeline for d1i8mh1:

• d1i8mh1 first appeared in SCOP 1.59
  
• d1i8mh1 appears in SCOP 1.71
  
• d1i8mh1 appears in SCOP 1.75
  
• d1i8mh1 appears in the current release, SCOPe 2.08