SCOPe 2.06: Domain d1hp0a1: 1hp0 A:2-327

Lineage for d1hp0a1 (1hp0 A:2-327)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.70: Nucleoside hydrolase [53589] (1 superfamily)
   core: 3 layers, a/b/a ; mixed beta-sheet of 8 strands, order 32145687; strand 7 is antiparallel to the rest

4. Superfamily c.70.1: Nucleoside hydrolase [53590] (2 families)

5. Family c.70.1.1: Nucleoside hydrolase [53591] (5 proteins)
   automatically mapped to Pfam PF01156

6. Protein Inosine-adenosine-guanosine preferring nucleoside hydrolase [69587] (1 species)

7. Species Trypanosoma vivax [TaxId:5699] [69588] (5 PDB entries)

8. Domain d1hp0a1: 1hp0 A:2-327 [65900]
   Other proteins in same PDB: d1hp0a2, d1hp0b2
   complexed with ad3, ca

Details for d1hp0a1

PDB Entry: 1hp0, 2.1 Å

PDB Description: crystal structure of an inosine-adenosine-guanosine-preferring nucleoside hydrolase from trypanosoma vivax in complex with the substrate analogue 3-deaza-adenosine

PDB Compounds: (A:) inosine-adenosine-guanosine-preferring nucleoside hydrolase

SCOPe Domain Sequences for d1hp0a1:

Sequence, based on SEQRES records:

>d1hp0a1 c.70.1.1 (A:2-327) Inosine-adenosine-guanosine preferring nucleoside hydrolase {Trypanosoma vivax [TaxId: 5699]}
aknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnnm
nlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqqll
adlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstdg
taewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgtm
wamcthcellrdgdgyyawdaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaen
ypltfvarnpeaeffldmllrsarac

Sequence, based on observed residues (ATOM records):

>d1hp0a1 c.70.1.1 (A:2-327) Inosine-adenosine-guanosine preferring nucleoside hydrolase {Trypanosoma vivax [TaxId: 5699]}
aknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnnm
nlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqqll
adlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstdg
taewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgtm
wamcthgyyawdaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaenypltfvar
npeaeffldmllrsarac

Timeline for d1hp0a1:

• d1hp0a1 first appeared in SCOP 1.59, called d1hp0a_
  
• d1hp0a1 was called d1hp0a_ in SCOPe 2.05
  
• d1hp0a1 appears in SCOPe 2.07
  
• d1hp0a1 appears in the current release, SCOPe 2.08