SCOPe 2.06: Domain d1hnna_: 1hnn A:

Lineage for d1hnna_ (1hnn A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.15: Arylamine N-methyltransferase [69547] (3 proteins)
   automatically mapped to Pfam PF01234

6. Protein Phenylethanolamine N-methyltransferase, PNMTase [69548] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69549] (8 PDB entries)

8. Domain d1hnna_: 1hnn A: [65895]
   complexed with sah, skf

Details for d1hnna_

PDB Entry: 1hnn, 2.4 Å

PDB Description: crystal structure of human pnmt complexed with sk&f 29661 and adohcy(sah)

PDB Compounds: (A:) Phenylethanolamine N-methyltransferase

SCOPe Domain Sequences for d1hnna_:

Sequence; same for both SEQRES and ATOM records:

>d1hnna_ c.66.1.15 (A:) Phenylethanolamine N-methyltransferase, PNMTase {Human (Homo sapiens) [TaxId: 9606]}
avasayqrfepraylrnnyapprgdlcnpngvgpwklrclaqtfatgevsgrtlidigsg
ptvyqllsacshfeditmtdflevnrqelgrwlqeepgafnwsmysqhacliegkgecwq
dkerqlrarvkrvlpidvhqpqplgagspaplpadalvsafcleavspdlasfqraldhi
ttllrpgghllligaleeswylagearltvvpvseeevrealvrsgykvrdlrtyimpah
lqtgvddvkgvffawaqkvgl

Timeline for d1hnna_:

• d1hnna_ first appeared in SCOP 1.59
  
• d1hnna_ appears in SCOPe 2.05
  
• d1hnna_ appears in SCOPe 2.07
  
• d1hnna_ appears in the current release, SCOPe 2.08